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期刊论文 5

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2022 2

2017 2

2012 1

关键词

分析滤波器;线性预测;窄带语音水印;通带激励替代;能量规范化;谱包络成形;合成滤波器 1

单目标渐进法 1

双目标渐进法 1

极差标准化 1

生态文明发展水平 1

省域生态文明评估 1

驾驶行为;标准化;门控自编码器;定量评价 1

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Progress in tumor vascular normalization for anticancer therapy: challenges and perspectives

null

《医学前沿(英文)》 2012年 第6卷 第1期   页码 67-78 doi: 10.1007/s11684-012-0176-8

摘要:

Antitumor angiogenic therapy has been shown promising in the treatment of several advanced cancers since the approval of the first antiangiogenic drug Avastin in 2004. Although the current antiangiogenic drugs reduce the density of tumor blood vessels and result in tumor shrinkage at the early stage of treatment, recent studies have shown that antiangiogenic therapy has transient and insufficient efficacy, resulting in tumor recurrence in patients after several months of treatment. Blockage of blood and oxygen supplies creates a hypoxic and acidic microenvironment in the tumor tissues, which fosters tumor cells to become more aggressive and metastatic. In 2001, Jain proposed tumor vascular normalization as an alternative approach to treating cancers based on the pioneering work on tumor blood vessels by several other researchers. At present, normalizing the disorganized tumor vasculature, rather than disrupting or blocking them, has emerged as a new option for anticancer therapy. Preclinical and clinical data have shown that tumor vascular normalization using monoclonal antibodies, proteins, peptides, small molecules, and pericytes resulted in decreased tumor size and reduced metastasis. However, current tumor vascular normalizing drugs display moderate anticancer efficacy. Accumulated data have shown that a variety of vasculogenic/angiogenic tumor cells and genes play important roles in tumor neovascularization, growth, and metastasis. Therefore, multiple-targeting of vasculogenic tumor cells and genes may improve the efficacy of tumor vascular normalization. To this end, the combination of antiangiogenic drugs with tumor vascular normalizing therapeutics, as well as the integration of Western medicine with traditional Chinese medicine, may provide a good opportunity for discovering novel tumor vascular normalizing drugs for an effective anticancer therapy.

关键词: angiogenesis     vasculogenesis     neovascularization     tumor     vasculature     normalization     traditional Chinese medicine    

基于门控自编码器的驾驶行为量化评价标准化策略 Research Articles

何欣,张哲,许力,俞佳培

《信息与电子工程前沿(英文)》 2022年 第23卷 第3期   页码 452-462 doi: 10.1631/FITEE.2000667

摘要: 在评估驾驶风格时,对驾驶行为的标准化至关重要。本文对车辆的纵向控制进行了研究。通过归一化任务将不同环境中的驾驶行为映射到统一条件下。前人工作采用必要的驾驶员模型进行驾驶循环测试;与这种基于模型的方法不同,我们提出的方法在遵循标准速度曲线时使用自动编码器直接对驾驶行为进行标准化。为确保车速和驾驶行为之间满足正相关约束条件,在编码器和解码器之间设计了门控函数。所提方法无需模型且高效。测试结果验证了该方法与已有方法的一致性。同时,测试了其在驾驶行为和燃料消耗分析的定量评估中的应用。仿真结果验证了所提方法的有效性。

关键词: 驾驶行为;标准化;门控自编码器;定量评价    

Modeling, simulation, and prediction of global energy indices: a differential approach

Stephen Ndubuisi NNAMCHI, Onyinyechi Adanma NNAMCHI, Janice Desire BUSINGYE, Maxwell Azubuike IJOMAH, Philip Ikechi OBASI

《能源前沿(英文)》 2022年 第16卷 第2期   页码 375-392 doi: 10.1007/s11708-021-0723-6

摘要: Modeling, simulation, and prediction of global energy indices remain veritable tools for econometric, engineering, analysis, and prediction of energy indices. Thus, this paper differentially modeled, simulated, and non-differentially predicated the global energy indices. The state-of-the-art of the research includes normalization of energy indices, generation of differential rate terms, and regression of rate terms against energy indices to generate coefficients and unexplained terms. On imposition of initial conditions, the solution to the system of linear differential equations was realized in a Matlab environment. There was a strong agreement between the simulated and the field data. The exact solutions are ideal for interpolative prediction of historic data. Furthermore, the simulated data were upgraded for extrapolative prediction of energy indices by introducing an innovative model, which is the synergy of deflated and inflated prediction factors. The innovative model yielded a trendy prediction data for energy consumption, gross domestic product, carbon dioxide emission and human development index. However, the oil price was untrendy, which could be attributed to odd circumstances. Moreover, the sensitivity of the differential rate terms was instrumental in discovering the overwhelming effect of independent indices on the dependent index. Clearly, this paper has accomplished interpolative and extrapolative prediction of energy indices and equally recommends for further investigation of the untrendy nature of oil price.

关键词: energy indices     differential model     normalization     simulation     inflation/deflation     predictive factor and prediction rate    

一种基于子带激励替换的窄带语音水印算法 Article

Wei LIU, Ai-qun HU

《信息与电子工程前沿(英文)》 2017年 第18卷 第5期   页码 627-643 doi: 10.1631/FITEE.1601503

摘要: 本文建议了一种新的窄带语音水印算法,该算法将部分语音信号替换为一个经过幅度调节和频谱成形的隐蔽信号。文中从理论上证明了若仅对一小部分载体语音作修改,则不但可以建立一个用于隐蔽通信的理想信道模型,而且还能确保隐藏信号的不可感知性和带水印信号的可懂度。在此基础上,文中建议了一个实际的系统模型。在嵌入器中,使用了能量规范化准则,使得通带水印信号的能量与原始通带语音激励信号的能量相等,然后使用合成滤波器来对该水印信号进行频谱成形。在提取器中,先用带通滤波器去除带外信号,然后用分析滤波器对失真进行补偿。实验结果显示,本文建议算法的数据速率可达400 bits/s,具有更佳的带宽效率,且有良好的不可感知性。此外,该算法对实际应用中的各种攻击也是顽健的。

关键词: 分析滤波器;线性预测;窄带语音水印;通带激励替代;能量规范化;谱包络成形;合成滤波器    

基于双目标渐进法的中国省域生态文明发展水平评估研究

解钰茜,张林波,罗上华,杨娇,李芬,王德旺

《中国工程科学》 2017年 第19卷 第4期   页码 60-66 doi: 10.15302/J-SSCAE-2017.04.010

摘要:

本文构建了包含4个领域、10个目标、25个指标的省域生态文明发展水平评估指标体系。在对比和改进现有数据标准化处理方法的基础上,提出双目标渐进法对评价指标进行归一化处理,并采用综合加权指数法对2014年我国的31个省、自治区、直辖市的生态文明发展水平进行评估。结果显示,我国生态文明发展水平较低,东南沿海地区生态文明发展水平高于中西部地区。总体来看,目前我国整体经济社会建设成效显著,但我国生态文明发展水平与预期目标及国际水平相比还有一定差距,因此在生态环境保护、工业污染控制、产业优化和资源高效利用方面还需加强。

关键词: 生态文明发展水平     省域生态文明评估     双目标渐进法     单目标渐进法     极差标准化    

标题 作者 时间 类型 操作

Progress in tumor vascular normalization for anticancer therapy: challenges and perspectives

null

期刊论文

基于门控自编码器的驾驶行为量化评价标准化策略

何欣,张哲,许力,俞佳培

期刊论文

Modeling, simulation, and prediction of global energy indices: a differential approach

Stephen Ndubuisi NNAMCHI, Onyinyechi Adanma NNAMCHI, Janice Desire BUSINGYE, Maxwell Azubuike IJOMAH, Philip Ikechi OBASI

期刊论文

一种基于子带激励替换的窄带语音水印算法

Wei LIU, Ai-qun HU

期刊论文

基于双目标渐进法的中国省域生态文明发展水平评估研究

解钰茜,张林波,罗上华,杨娇,李芬,王德旺

期刊论文