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Frontiers of Medicine >> 2014, Volume 8, Issue 4 doi: 10.1007/s11684-014-0385-4

The evolution of surgical and medical treatment of aortic root aneurysm

1. Oxford Heart Centre, John Radcliffe Hospital, Oxford OX3 9DU, UK.

2. Oxford Echo Core Lab, NDCLS, Radcliffe Department of Medicine, University of Oxford, Oxford OX3 9DU, UK.

3. Academic Department of Cardiac Surgery, Royal Brompton Hospital, London SW3 6NP, UK.

4. Department of Ultrasonography, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China

Available online: 2014-12-18

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Since first report of aortic root replacement in 1968, the surgical risk and long term outcome of patients with aortic root aneurysm have been continuously improving. In the last 30 years, the surgical approach is also evolving towards more valve conservation with prophylactical intervention at an earlier clinical stage. Translational research has also led to emerging surgical innovation and new drug therapy. Their efficacies are currently under vigorous clinical trials and evaluations.

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