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Frontiers of Medicine >> 2021, Volume 15, Issue 4 doi: 10.1007/s11684-020-0780-y
Targeting “undruggable” c-Myc protein by synthetic lethality
. Division of Genome Medicine and Cancer Institute (Key Laboratory of Cancer Prevention and Intervention, China National Ministry of Education), the Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310009, China;.. Institute of Genetics, Zhejiang University and Department of Genetics, Zhejiang University School of Medicine, Hangzhou 310058, China;.. Zhejiang Laboratory for Systems & Precision Medicine, Zhejiang University Medical Center, Hangzhou 311121, China
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Keywords
synthetic lethality ; undruggable ; transcription factor ; c-Myc
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