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Frontiers of Medicine >> 2022, Volume 16, Issue 4 doi: 10.1007/s11684-021-0844-7
Long-term correction of hemorrhagic diathesis in hemophilia A mice by an AAV-delivered hybrid FVIII composed of the human heavy chain and the rat light chain
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Keywords
hemophilia A ; adeno-associated virus (AAV) ; human/rat hybrid factor VIII ; gene therapy ; dual chain strategy
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