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Adenovirus-mediated antisense ERK2 gene therapy ameliorates chronic allograft nephropathy in a rat model

Zhao DING, Zhishui CHEN, Xilin CHEN, Ming CAI, Hui GUO, Nianqiao GONG

Frontiers of Medicine 2009, Volume 3, Issue 2,   Pages 204-210 doi: 10.1007/s11684-009-0039-0

Abstract: To investigate the effect and underlying mechanism of adenovirus-mediated antisense ERK2 (Adanti-ERK2The recipients were divided into three groups: (1) empty control group; (2) vector control group; (3)Adanti-ERK2 gene therapy protects the renal allograft and attenuates graft fibrosis, which may be correlated

Keywords： anti-ERK2     renal transplantation     epithelial mesenchymal transition     chronic allograft nephropathy    

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Anti-β glycoprotein I antibodies in complex with β2 glycoprotein I induce platelet activation via tworeceptors: apolipoprotein E receptor 2' and glycoprotein I bα

Wenjing Zhang,Fei Gao,Donghe Lu,Na Sun,Xiaoxue Yin,Meili Jin,Yanhong Liu

Frontiers of Medicine 2016, Volume 10, Issue 1,   Pages 76-84 doi: 10.1007/s11684-015-0426-7

Abstract:

Anti-β2 glycoprotein I (anti-β2GP I ) antibodies are importantba (GP I bα) in platelet activation induced by the anti-β2GP I /β2anti-β2GP I /β2GP I complex and plateletsOur results revealed that the anti-β2GP I /β2GP I complex was able toResults showed that the anti-β2GP I /β2GP I complex induced platelet

Keywords： anti-β2GP I /β2GP I complex     platelet     GP I bα     apoER2'     thrombosis    

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Modulatory effect on dyslipidemia and anti-atherosclerotic function of in newly diagnosed type 2 diabetes

SUN Mingxiao, WANG Yao, CHI Jiamin

Frontiers of Medicine 2008, Volume 2, Issue 2,   Pages 174-177 doi: 10.1007/s11684-008-0032-z

Abstract: modulatory effect of on dyslipidemia and the preventive effect on atherosclerosis in newly diagnosed type 2prospective clinical trial was conducted to test the effectiveness of in selected 201 newly diagnosed type 2The study demonstrates that therapy is effective on modulating dyslipidemia in newly diagnosed type 2
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Anti-β2GPI/β2GPI complexes induce platelet activation and promote thrombosis via

Wenjing Zhang, Caijun Zha, Xiumin Lu, Ruichun Jia, Fei Gao, Qi Sun, Meili Jin, Yanhong Liu

Frontiers of Medicine 2019, Volume 13, Issue 6,   Pages 680-689 doi: 10.1007/s11684-018-0673-5

Abstract: Anti- glycoprotein I (anti- GPI) antibodies are important contributors to the development of thrombosisAnti- GPI antibody complexes with GPI are well known to activate monocytes and endothelial cells viaBy contrast, the interaction of anti- GPI/ GPI complexes with platelets has not been extensively studiedFurthermore, SB203580 inhibits anti- GPI/ GPI complex-induced platelet activation.Thrombus formation decreased in mice after treatment with anti- GPI/ GPI complexes.

Keywords： anti-   

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QUANTITATIVE STUDY ON ANTI-PEST ACTIVITY OF NATURAL PRODUCTS BASED ON VISUALIZATION FRAMEWORK OF KNOWLEDGE

Frontiers of Agricultural Science and Engineering 2023, Volume 10, Issue 2,   Pages 306-332 doi: 10.15302/J-FASE-2023488

Abstract:

● Using visual analysis to predict the trend of natural product pest resistance.

Keywords： anti-pest activity     crop protection     insect pest     natural product     visual analysis    

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Dihydroartemisinin increased the abundance of by YAP1 depression that sensitizes hepatocellular carcinoma to anti-PD

Frontiers of Medicine 2023, Volume 17, Issue 4,   Pages 729-746 doi: 10.1007/s11684-022-0978-2

Abstract: The effect of anti-programmed cell death 1 (anti-PD-1) immunotherapy is limited in patients with hepatocellularThe response to anti-PD-1 treatment is associated with A. muciniphila abundance in many tumorsHere, anti-PD-1 treatment decreased A. muciniphila abundance in the colon, but increased YAP1Yap1 knockout enhanced anti-PD-1 efficacy.Our findings suggested that the combination anti-PD-1 with DHA is an effective strategy for liver tumor

Keywords： hepatocellular carcinoma     YAP1     Akkermansia muciniphila     anti-PD-1     dihydroartemisinin     bile acid    

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A modular cable-driven humanoid arm with anti-parallelogram mechanisms and Bowden cables

Frontiers of Mechanical Engineering 2023, Volume 18, Issue 1, doi: 10.1007/s11465-022-0722-2

Abstract: This paper proposes a novel modular cable-driven humanoid arm with anti-parallelogram mechanisms (APMs

Keywords： modular robotic arm     anti-parallelogram mechanism     Bowden cable     humanoid arm     lightweight joint design    

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Anti-biofouling strategies for implantable biosensors of continuous glucose monitoring systems

Frontiers of Chemical Science and Engineering 2023, Volume 17, Issue 12,   Pages 1866-1878 doi: 10.1007/s11705-023-2340-x

Abstract: review, research efforts over the past few years to mitigate the immune responses by enhancing the anti-biofoulinglayers on the biosensor surface, such as drug-releasing membranes, hydrogels, hydrophilic membranes, anti-biofoulinginformation, which is likely to aid in the research and development of novel CGM systems with profound anti-biofouling

Keywords： implantable glucose biosensor     anti-biofouling     continuous glucose monitoring     immune responses    

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Preparation and characterization of poly (vinylidene fluoride)/TiO

Weiying LI, Xiuli SUN, Chen WEN, Hui LU, Zhiwei WANG

Frontiers of Environmental Science & Engineering 2013, Volume 7, Issue 4,   Pages 492-502 doi: 10.1007/s11783-012-0407-x

Abstract: Moreover, permeate flux, retention factor, porosity, contact angle and anti-fouling tests were carried

Keywords： poly(vinylidene fluoride) (PVDF) membrane     nano-TiO2     anti-fouling performance     water treatment    

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Lignin-derived dual-function red light carbon dots for hypochlorite detection and anti-counterfeiting

Frontiers of Chemical Science and Engineering 2023, Volume 17, Issue 7,   Pages 966-975 doi: 10.1007/s11705-022-2244-1

Abstract: By taking advantage of the large sp2 hybrid domain of lignin and introducing amino functionalCompared with green and blue fluorescent materials, red SPN-CDs have desirable anti-interference properties

Keywords： alkali lignin     red light carbon dots     hypochlorite     encryption and anti-counterfeiting    

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Preparation of reverse osmosis membrane with high permselectivity and anti-biofouling properties for

Frontiers of Environmental Science & Engineering 2022, Volume 16, Issue 7, doi: 10.1007/s11783-021-1497-0

Abstract:

• Nanoparticle incorporation and anti-biofouling grafting were integrated

Keywords： Anti-biofouling grafting     Nanoparticle incorporation     Sterilization rates     Water flux     Water flux recovery    

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Small-molecule anti-COVID-19 drugs and a focus on China’s homegrown mindeudesivir (VV116)

Frontiers of Medicine doi: 10.1007/s11684-023-1037-3

Abstract: tremendous efforts to develop therapeutic agents that target severe acute respiratory syndrome coronavirus 2To date, four domestically developed oral anti-COVID-19 drugs have been granted conditional market approvalwill expand our understanding and highlight the potential widespread application of China’s homegrown anti-COVID

Keywords： COVID-19     antiviral drugs     mindeudesivir    

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Improved dissolution and anti-inflammatory effect of ibuprofen by solid dispersion

Liyuan Chen, Qifeng Dang, Chengsheng Liu, Jun Chen, Lei Song, Xiguang Chen

Frontiers of Medicine 2012, Volume 6, Issue 2,   Pages 195-203 doi: 10.1007/s11684-012-0189-3

Abstract:

The purpose of this study was to improve the dissolution rate and anti-inflammatory effect of ibuprofenThe anti-inflammatory effect of SDBT was evaluated using the mouse ear edema test with xylene.SDBT displayed more significant anti-inflammatory effects than CT.The dissolution rate and anti-inflammatory effect of ibuprofen were significantly enhanced by the ibuprofen-urea

Keywords： ibuprofen     solid dispersion     physical mixture     dissolution     anti-inflammatory effect    

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Mobile CRISPR-Cas9 based anti-phage system in E. coli

Frontiers of Chemical Science and Engineering 2022, Volume 16, Issue 8,   Pages 1281-1289 doi: 10.1007/s11705-022-2141-7

Abstract: Here, we developed a mobile CRISPR-Cas9 based anti-phage system for bacteriophages defense in E. coli Two conjugative plasmids pGM1 (phosphoglucomutase 1) and pGM2 carrying one and two guide RNAs, respectivelyThe results showed that the pGM1 and pGM2 could decrease the phage infection rate to 1.6% and 0.2% respectivelyFor preventing phage infection in E. coli, the pGM2 decreased the phage infection rate to 0.1%

Keywords： phage infections     anti-phage     CRISPR-Cas9     conjugative transfer     synthetic biology    

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Impact of Recent Regional Wars on Requirements of Ground based Air Defense Radars

Peng Jiating

Strategic Study of CAE 1999, Volume 1, Issue 2,   Pages 19-23

Abstract: targets as the cruise missile, attack helicopter, lowaltitude aircraft (including stealthy ones) and anti-radiation

Keywords： low altitude     air defense radar     anti-stealth     anti-cruise missile     anti-antiradiation missile    

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Title Author Date Type Operation

Adenovirus-mediated antisense ERK2 gene therapy ameliorates chronic allograft nephropathy in a rat model

Zhao DING, Zhishui CHEN, Xilin CHEN, Ming CAI, Hui GUO, Nianqiao GONG

Journal Article

Anti-β glycoprotein I antibodies in complex with β2 glycoprotein I induce platelet activation via tworeceptors: apolipoprotein E receptor 2' and glycoprotein I bα

Wenjing Zhang,Fei Gao,Donghe Lu,Na Sun,Xiaoxue Yin,Meili Jin,Yanhong Liu

Journal Article

Modulatory effect on dyslipidemia and anti-atherosclerotic function of in newly diagnosed type 2 diabetes

SUN Mingxiao, WANG Yao, CHI Jiamin

Journal Article

Anti-β2GPI/β2GPI complexes induce platelet activation and promote thrombosis via

Wenjing Zhang, Caijun Zha, Xiumin Lu, Ruichun Jia, Fei Gao, Qi Sun, Meili Jin, Yanhong Liu

Journal Article

QUANTITATIVE STUDY ON ANTI-PEST ACTIVITY OF NATURAL PRODUCTS BASED ON VISUALIZATION FRAMEWORK OF KNOWLEDGE

Journal Article

Dihydroartemisinin increased the abundance of by YAP1 depression that sensitizes hepatocellular carcinoma to anti-PD

Journal Article

A modular cable-driven humanoid arm with anti-parallelogram mechanisms and Bowden cables

Journal Article

Anti-biofouling strategies for implantable biosensors of continuous glucose monitoring systems

Journal Article

Preparation and characterization of poly (vinylidene fluoride)/TiO

Weiying LI, Xiuli SUN, Chen WEN, Hui LU, Zhiwei WANG

Journal Article

Lignin-derived dual-function red light carbon dots for hypochlorite detection and anti-counterfeiting

Journal Article

Preparation of reverse osmosis membrane with high permselectivity and anti-biofouling properties for

Journal Article

Small-molecule anti-COVID-19 drugs and a focus on China’s homegrown mindeudesivir (VV116)

Journal Article

Improved dissolution and anti-inflammatory effect of ibuprofen by solid dispersion

Liyuan Chen, Qifeng Dang, Chengsheng Liu, Jun Chen, Lei Song, Xiguang Chen

Journal Article

Mobile CRISPR-Cas9 based anti-phage system in E. coli

Journal Article

Impact of Recent Regional Wars on Requirements of Ground based Air Defense Radars

Peng Jiating

Journal Article