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Impact of diabetes and its treatments on skeletal diseases
Wenbo Yan, Xin Li
Frontiers of Medicine 2013, Volume 7, Issue 1, Pages 81-90 doi: 10.1007/s11684-013-0243-9
Keywords: diabetes bone osteoporosis osteoarthritis
-Derived miR162a Functions on Osteoporosis Through Directly Promoting Osteoblast Formation
Chunyan Gu,Xichao Yu,Xiaozhu Tang,Leilei Gong,Jingquan Tan,Yuanjiao Zhang,Huili Zheng,Ze Wang,Chenqian Zhang,Yejin Zhu,Zuojian Zhou,Heming Yu,Kai Xu,Jinao Duan,Xiaosong Gu,Ye Yang,
Engineering doi: 10.1016/j.eng.2023.09.007
Keywords: Traditional Chinese medicine Lycium barbarum L miR162a Osteoporosis Nuclear receptor corepressor Transgenic
Medical applications of phytoestrogens from the Thai herb
Suchinda Malaivijitnond
Frontiers of Medicine 2012, Volume 6, Issue 1, Pages 8-21 doi: 10.1007/s11684-012-0184-8
Pueraria mirifica Airy Shaw et Suvatabandhu is a medicinal plant endemic to Thailand. It has been used in Thai folklore medicine for its rejuvenating qualities in aged women and men for nearly one hundred years. Indeed, it has been claimed that P. mirifica contains active phytoestrogens (plant substances with estrogen-like activity). Using high performance liquid chromatography, at least 17 phytoestrogens, mainly isoflavones, have been isolated. Thus, fairly considerable scientific researches, both in vitro in cell lines and in vivo in various species of animals including humans, have been conducted to date to address its estrogenic activity on the reproductive organs, bones, cardiovascular diseases and other climacteric related symptoms. The antioxidative capacity and antiproliferative effect on tumor cell lines have also been assessed. In general, P. mirifica could be applicable for preventing, or as a therapeutic for, the symptoms related to estrogen deficiency in menopausal women as well as in andropausal men. However, the optimal doses for each desirable effect and the balance to avoid undesired side effects need to be calculated before use.
Keywords: white Kwao Krua miroestrol estrogenic activity reproduction osteoporosis breast cancer Alzheimer
Frontiers of Medicine 2022, Volume 16, Issue 3, Pages 496-506 doi: 10.1007/s11684-021-0828-7
Keywords: XGBoost deep neural network healthcare risk prediction
Mechanisms of “kidney governing bones” theory in traditional Chinese medicine
Dahong Ju,Meijie Liu,Hongyan Zhao,Jun Wang
Frontiers of Medicine 2014, Volume 8, Issue 3, Pages 389-393 doi: 10.1007/s11684-014-0362-y
Keywords: kidney governing bones kidney deficiency marrow osteoporosis neuroendocrine-immune network osteoclast
Title Author Date Type Operation
-Derived miR162a Functions on Osteoporosis Through Directly Promoting Osteoblast Formation
Chunyan Gu,Xichao Yu,Xiaozhu Tang,Leilei Gong,Jingquan Tan,Yuanjiao Zhang,Huili Zheng,Ze Wang,Chenqian Zhang,Yejin Zhu,Zuojian Zhou,Heming Yu,Kai Xu,Jinao Duan,Xiaosong Gu,Ye Yang,
Journal Article
Hybrid deep learning model for risk prediction of fracture in patients with diabetes and osteoporosis
Journal Article