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HBV cccDNA 1

HBV intrauterine transmission 1

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Impact of HBV replication in peripheral blood mononuclear cell on HBV intrauterine transmission

Xiaohong Shi, Xuefei Wang, Xixi Xu, Yongliang Feng, Shuzhen Li, Shuying Feng, Bo Wang, Suping Wang

Frontiers of Medicine 2017, Volume 11, Issue 4,   Pages 548-553 doi: 10.1007/s11684-017-0597-5

Abstract: determined the effect of hepatitis B virus (HBV) replication in peripheral blood mononuclear cell (PBMCWithin 24 h after birth, HBV serological markers, serum HBV DNA, PBMC HBV relaxed circular DNA (rcDNAThe relationship between HBV replication in PBMC and HBV intrauterine transmission was examined throughThe positivities of PBMC HBV rcDNA and cccDNA in the HBsAg-positive mothers were 36.67% (55/150) andMaternal serum HBeAg was a risk factor of PBMC HBV rcDNA (OR= 3.896, 95% CI: 1.929–7.876) and PBMC

Keywords： PBMC     HBV cccDNA     HBV rcDNA     HBV intrauterine transmission    

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Impact of HBV replication in peripheral blood mononuclear cell on HBV intrauterine transmission

Xiaohong Shi, Xuefei Wang, Xixi Xu, Yongliang Feng, Shuzhen Li, Shuying Feng, Bo Wang, Suping Wang

Journal Article