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Effects of modafinil on vestibular function during 24 hour sleep deprivation

ZHAN Hao, XIE Sujiang, JIA Hongbo, WEI Sihuang, JING Baisheng

Frontiers of Medicine 2007, Volume 1, Issue 2, Pages 226-229 doi: 10.1007/s11684-007-0044-0

Abstract: The aim of this research was to investigate the effects of modafinil, a new wake-promoting agent, onInitially, 200 mg dose of modafinil was given, and one week later, a matching placebo was administeredgroup decreased during 24 h SD, especially at 01:00 05:00 on the second day, while OKN gains in the modafinilThere were no significant differences in the other vestibular functional indices between the modafinilThe 24 h SD can influence vestibular function to a certain degree, but modafinil may improve OKN.

Keywords： VVOR modafinil Vestibular function vestibular functional Initially