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A reignited debate over the cell(s) of origin for glioblastoma and its clinical implications

Xiaolin Fan, Yanzhen Xiong, Yuan Wang

Frontiers of Medicine 2019, Volume 13, Issue 5,   Pages 531-539 doi: 10.1007/s11684-019-0700-1

Abstract: Therefore, identification of the cell(s) of origin for GBM—the normal cell or cell type that acquiresNeural stem cells and oligodendrocyte precursor cells are the two major candidates for the cell(s) of originhuman samples have reignited the longstanding debate over which cells are the clinically more relevant origin

Keywords： glioblastoma     cell(s) of origin     neural stem cells     oligodendrocyte precursor cells     subventricular zone    

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In quest of the origin of ancient northern city of China: An implication from the Book of Odes

DAI Fudong

Frontiers of Structural and Civil Engineering 2007, Volume 1, Issue 4,   Pages 389-392 doi: 10.1007/s11709-007-0052-9

Abstract: Sorting out some paragraphs in (collection of the earliest poetry in China), this paper makes analysis of the formation, construction process and technology of the ancient northern city of China. Relevan

Keywords： analysis     construction     formation     collection     paragraphs    

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Russian school of the theory and geometry of gearing: Its origin and golden period (1935 --1975)

Dmitry BABICHEV,Sergey LAGUTIN,Natalya BARMINA

Frontiers of Mechanical Engineering 2016, Volume 11, Issue 1,   Pages 44-59 doi: 10.1007/s11465-015-0360-z

Abstract:

During the second half of the twentieth century, Soviet scientists were among the world leaders in the theory and geometry of gearing or the theoretical fundamentals of designing gears and gear-cutting tools. The authors of the current paper review works related to the development of the theory of gearing (TG) written in Russian from the mid-1930s to the present. Overall, the review covers more than 400 publications of nearly 200 authors (among more than 1000 studied works). This review involves some works on gear strength and accuracy to attract more experts.

This paper presents a short list of works from the seventeenth century to the nineteenth century and discusses the basic concepts of the TG. This paper also includes a review of more than 160 papers in Russian for the period of 1935–1975, which is the “golden age” of the TG. The main features and achievements during this period are also considered.

The distinctive feature of this review is the use of diagrams that visually present TG experts and the dates and themes of their published works. The diagrams also show the following aspects: 1) The most popular and important themes in a specific period, 2) the most important publications on the themes of interest to readers, and 3) the direction of the works and scope of interests of every researcher.

Keywords： theory of gearing (TG)     gear geometry     generating surface     gear synthesis     gear analysis    

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The Origin and System Analysis of Harmonious Management for Engineering

Mao-guang Lin,Qian-kun Wang,Hua-tao Peng,Yu-dong Wang

Frontiers of Engineering Management 2015, Volume 2, Issue 3,   Pages 241-248 doi: 10.15302/J-FEM-2015040

Abstract: Engineering is a production activity aimed at increasing people’s utility; however, serious crises are frequently reported to be caused by engineering constructions, both for nature and human beings. Based on engineering theories of philosophy, systems and ecology, this paper analyzed the prevailing defects of traditional project management approaches, explored the importance of harmony in engineering and engineering management, and discussed the developmental inevitability, concept connotation and system structure of harmonious management for engineering.

Keywords： engineering     harmony     management    

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Research on Origin of Traditional Chinese Medicine

Fu Youfeng

Strategic Study of CAE 2006, Volume 8, Issue 9,   Pages 1-12

Abstract: author has explored the relationship between epidemic disease (especially bubonic plague) and medicine origin

Keywords： world medicine history     history of TCM     medicine origin     plague     cholera     smallpox     comparative medicine    

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From SARS to MERS: evidence and speculation

Hainv Gao,Hangping Yao,Shigui Yang,Lanjuan Li

Frontiers of Medicine 2016, Volume 10, Issue 4,   Pages 377-382 doi: 10.1007/s11684-016-0466-7

Abstract:

The Middle East respiratory syndrome coronavirus (MERS-CoV) is a novel zoonotic pathogen. In 2012, the infectious outbreak caused by MERS-CoV in Saudi Arabia has spread to more than 1600 patients in 26 countries, resulting in over 600 deaths. Without a travel history, few clinical and radiological features can reliably differentiate MERS from SARS. But in real world, comparing with SARS, MERS presents more vaguely defined epidemiology, more severe symptoms, and higher case fatality rate. In this review, we summarize the recent findings in the field of MERS-CoV, especially its molecular virology, interspecies mechanisms, clinical features, antiviral therapies, and the further investigation into this disease. As a newly emerging virus, many questions are not fully answered, including the exact mode of transmission chain, geographical distribution, and animal origins. Furthermore, a new protocol needs to be launched to rapidly evaluate the effects of unproven antiviral drugs and vaccine to fasten the clinical application of new drugs.

Keywords： middle east respiratory syndrome     animal origin     cross-species transmission     monoclonal antibody    

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The origin and system analysis of harmonious management for engineering

Lin Maoguang,Wang Qiankun,Peng Huatao,Wang Yudong

Strategic Study of CAE 2014, Volume 16, Issue 10,   Pages 15-21

Abstract:

Engineering is a producing activity on purpose of people’s utility. And various engineering constructions have caused serious crisis to the nature and human ourselves. Based on the thoughts such as engineering philosophy，engineering system and engineering ecology，this paper discussed the development inevitability，concept connotation and the system structure of harmonious management for engineering through dissecting the harmony needs of engineering and engineering management，especially analyzing the defects of engineering project management on the developing stage of engineering management.

Keywords： engineering     harmony     management    

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Immunohistochemical characterization of hepatic stem cell-related cells in developing human liver

XU Jun, HU Yong, WANG Jian, ZHANG Taiping, ZHOU Ji, YU Hongyu

Frontiers of Medicine 2007, Volume 1, Issue 3,   Pages 264-268 doi: 10.1007/s11684-007-0050-2

Abstract: It is significant to investigate the immunohistochemical expression for better understanding of the originhepatic cord cells begin to differentiate into hepatocytes and abundant HSCs remain in ductal plate (the originThese indirectly support the hypothesis about the location and origin of HSCs in liver valley hypothesis

Keywords： origin     Little     mesenchymal tissue     cords/mesenchymal tissue     CD34    

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Core Metabolic Features and Hot Origin of Bathyarchaeota Article

Xiaoyuan Feng, Yinzhao Wang, Rahul Zubin, Fengping Wang

Engineering 2019, Volume 5, Issue 3,   Pages 498-504 doi: 10.1016/j.eng.2019.01.011

Abstract: This work reveals the core metabolic features of Bathyarchaeota, and indicates a hot origin of this archaeal

Keywords： Bathyarchaeota     Metagenomics     Comparative genomics     Hyperthermophilic adaptation    

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The Origin of Traditional Chinese Medicine and Thinking on Chinese Medicine Development

Wang Wenkui,Wang Feng,Wang Ling

Strategic Study of CAE 2006, Volume 8, Issue 4,   Pages 1-11

Abstract:

Although the TCM has developed a profound theory system and a fame of outstanding advantage in curative effect, it seems that the TCM is not quite adaptable to the development and requirement of the modem society.

A principle of “Adopting the advanced part of Western medicine to serve the TCM” should be adhered to for the traditional Chinese medicine. First, TCM should strive for a consensus of TCM theory which focuses on the guiding principles of “diagnosis and treatment based on an overall analysis of the illness and the patient's condition” and “the opposite principle of five internal organs”.Among these principles, “keeping relative balance of three internal systems” is a valuable guidance of the diagnosis and treatment theory. Secondly, macroscopic should be integrated with microscopic, totality with parts, phenomenology with materialism. A dialectical law should be applied to guide analysis. In treatment, adjustment and balance are basic principles. It is necessary not only prepare the medicine in advance according to the predicted disease of the year, but also adopt methods to restrict disease in advance. Basides, TCM dose type should be ameliorated in order to meet the needs of society.

Keywords： traditional Chinese medicine (TCM)     development course & status of TCM     adopting the advanced part of western medicine to serve the TCM     the dose type of traditional Chinese medicine    

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Desertification: China provides a solution to a global challenge

Yingshuang BAO, Leilei CHENG, Yanfeng BAO, Liu YANG, Lina JIANG, Chao LONG, Zhe KONG, Peng PENG, Jun XIAO, Qi LU

Frontiers of Agricultural Science and Engineering 2017, Volume 4, Issue 4,   Pages 402-413 doi: 10.15302/J-FASE-2017187

Abstract: Desertification has been caused by various factors and is a major environmental problem and development bottleneck faced by the world. It is also a serious threat to ecological security and to sustainable economic and social development. As a stubborn world problem, focused on by the United Nations 2030 sustainable development goal 15.3, China aims to combat desertification by implementing the “eight-column four-beam” strategy, and also suggest the “four-medicine” approach for global desertification governance. This includes the development of the United Nations Convention to Combat Desertification protocol, unified global compliance and compliance metrics; building a global observation network, and monitoring land changes based on remote sense; preparing the global natural desert (heritage) list, leaving the original deserts for future generations; initiating the global action of combating desertification, and striving to achieve a land degradation-neutral world by 2030.

Keywords： desertification     global governance     land degradation neutrality     LDN     origin     status     strategy     sustainable    

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Discussion on the Origin of Deep-fissure Zones at theSite of Pusiluo Dam，Yalongjiang River

Li Ping,Li Yuanjun,Yang Meie,Zhao Dongzhi

Strategic Study of CAE 2007, Volume 9, Issue 3,   Pages 11-20

Abstract:

The deep fissure zones have been discovered during the engineering investigation at Pusiluo dam-site, Yalongjiang River. The zones, located 100-200 meters beneath the ground, are separated by thick uninterrupted rock mass between the ground gravity unloading zone and the fissure zone. The occurrence of the deep fissure zone is similar to that of a group of NE directional faults in this area. The newest fault gouge was developed 27-90 thousand years ago and had horizontal, oblique, up-down scratches on the fissure surface. All these observable facts indicate that the deep fissure zone was perhaps caused by the recent activity of the faults,  which generated seismi waves and created the deep fissure zone when the stress of waves was larger than rock's tensile strength. The genesis of deep fissure zone has been observed in the ground nuclear explosion and rock dynamics experiment.

Keywords： Pusiluo dam-site     Yalongjiang River     deep fissure zone     gravity unloading and gravitygliding     active fault    

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Materials Design on the Origin of Gap States in a High-κ/GaAs Interface Article

Weichao Wang,Cheng Gong,Ka Xiong,Santosh K.C.,Robert M. Wallace,Kyeongjae Cho

Engineering 2015, Volume 1, Issue 3,   Pages 372-377 doi: 10.15302/J-ENG-2015052

Abstract:

Given the demand for constantly scaling microelectronic devices to ever smaller dimensions, a SiO2 gate dielectric was substituted with a higher dielectric-constant material, Hf(Zr)O2, in order to minimize current leakage through dielectric thin film. However, upon interfacing with high dielectric constant (high-κ) dielectrics, the electron mobility in the conventional Si channel degrades due to Coulomb scattering, surface-roughness scattering, remote-phonon scattering, and dielectric-charge trapping. III-V and Ge are two promising candidates with superior mobility over Si. Nevertheless, Hf(Zr)O2/III-V(Ge) has much more complicated interface bonding than Si-based interfaces. Successful fabrication of a high-quality device critically depends on understanding and engineering the bonding configurations at Hf(Zr)O2/III-V(Ge) interfaces for the optimal design of device interfaces. Thus, an accurate atomic insight into the interface bonding and mechanism of interface gap states formation becomes essential. Here, we utilize first-principle calculations to investigate the interface between HfO2 and GaAs. Our study shows that As−As dimer bonding, Ga partial oxidation (between 3+ and 1+) and Ga− dangling bonds constitute the major contributions to gap states. These findings provide insightful guidance for optimum interface passivation.

Keywords： high-mobility device     high-&kappa     /III-V interface     interfacial gap states     first-principle calculations    

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Natural Host–Environmental Media–Human: A New Potential Pathway of COVID-19 Outbreak Perspective

Miao Li, Yunfeng Yang, Yun Lu, Dayi Zhang, Yi Liu, Xiaofeng Cui, Lei Yang, Ruiping Liu, Jianguo Liu, Guanghe Li, Jiuhui Qu

Engineering 2020, Volume 6, Issue 10,   Pages 1085-1098 doi: 10.1016/j.eng.2020.08.010

Abstract:


Identifying the first infected case (patient zero) is key in tracing the origin of a virus;rdquo; We reason that the environmental quasi-host is likely to be a key node in helping recognize the originTherefore, we propose a new potential mechanism to trace the origin of the COVID-19 outbreak.

Keywords： Environmental quasi-host     Patient zero     SARS-CoV-2     Pathway     Origin of COVID-19    

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Title Author Date Type Operation

A reignited debate over the cell(s) of origin for glioblastoma and its clinical implications

Xiaolin Fan, Yanzhen Xiong, Yuan Wang

Journal Article

In quest of the origin of ancient northern city of China: An implication from the Book of Odes

DAI Fudong

Journal Article

Russian school of the theory and geometry of gearing: Its origin and golden period (1935 --1975)

Dmitry BABICHEV,Sergey LAGUTIN,Natalya BARMINA

Journal Article

The Origin and System Analysis of Harmonious Management for Engineering

Mao-guang Lin,Qian-kun Wang,Hua-tao Peng,Yu-dong Wang

Journal Article

Research on Origin of Traditional Chinese Medicine

Fu Youfeng

Journal Article

From SARS to MERS: evidence and speculation

Hainv Gao,Hangping Yao,Shigui Yang,Lanjuan Li

Journal Article

The origin and system analysis of harmonious management for engineering

Lin Maoguang,Wang Qiankun,Peng Huatao,Wang Yudong

Journal Article

Immunohistochemical characterization of hepatic stem cell-related cells in developing human liver

XU Jun, HU Yong, WANG Jian, ZHANG Taiping, ZHOU Ji, YU Hongyu

Journal Article

Core Metabolic Features and Hot Origin of Bathyarchaeota

Xiaoyuan Feng, Yinzhao Wang, Rahul Zubin, Fengping Wang

Journal Article

The Origin of Traditional Chinese Medicine and Thinking on Chinese Medicine Development

Wang Wenkui,Wang Feng,Wang Ling

Journal Article

Desertification: China provides a solution to a global challenge

Yingshuang BAO, Leilei CHENG, Yanfeng BAO, Liu YANG, Lina JIANG, Chao LONG, Zhe KONG, Peng PENG, Jun XIAO, Qi LU

Journal Article

Discussion on the Origin of Deep-fissure Zones at theSite of Pusiluo Dam，Yalongjiang River

Li Ping,Li Yuanjun,Yang Meie,Zhao Dongzhi

Journal Article

Materials Design on the Origin of Gap States in a High-κ/GaAs Interface

Weichao Wang,Cheng Gong,Ka Xiong,Santosh K.C.,Robert M. Wallace,Kyeongjae Cho

Journal Article

Natural Host–Environmental Media–Human: A New Potential Pathway of COVID-19 Outbreak

Miao Li, Yunfeng Yang, Yun Lu, Dayi Zhang, Yi Liu, Xiaofeng Cui, Lei Yang, Ruiping Liu, Jianguo Liu, Guanghe Li, Jiuhui Qu

Journal Article

Liu Bing: Genome Wide Similarity and Evolution Analysis: Exploring the Origin of Novel Coronavirus (2020

18 Aug 2022

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