Search | Engineering

Subscribe Submit

Home Journals Focus Achievement Fronts About Us 中文版

Resource Type

Journal Article 4

Year

2019 1

2018 1

2017 1

2009 1

Keywords

EPR effect 1

Raman spectroscopy 1

anodic arc discharge 1

bio-inspired 1

biomimetic 1

cancer therapy 1

drug delivery 1

graphene platelet networks 1

nanomedicine 1

plasma healing 1

platelet 1

platelet-mimicking delivery systems 1

platelets 1

protease-activated receptors 1

scanning electron microscopy 1

tumor-associated platelets 1

open ︾

Search scope:

排序： Display mode:

Expression of protease-activated receptors on platelets in healthy individuals

Rui ZHU, Lin SHEN

Frontiers of Medicine 2009, Volume 3, Issue 2, Pages 236-239 doi: 10.1007/s11684-009-0040-7

Abstract: This study aimed to investigate the expression of protease-activated receptors (PARs) on platelets inThe results showed that the average levels of PAR1 mRNA and PAR4 mRNA on platelets in healthy individuals

Keywords： protease-activated receptors platelet

HTML PDF Collect

Plasma-enabled healing of graphene nano-platelets layer

Xiuqi Fang, Carles Corbella, Denis B. Zolotukhin, Michael Keidar

Frontiers of Chemical Science and Engineering 2019, Volume 13, Issue 2, Pages 350-359 doi: 10.1007/s11705-018-1787-7

Abstract: Graphene platelet networks (GPNs) were deposited onto silicon substrates by means of anodic arc discharge ignited between two graphite electrodes. Substrate temperature and pressure of helium atmosphere were optimized for the production of the carbon nanomaterials. The samples were modified or destroyed with different methods to mimic typical environments responsible of severe surface degradation. The emulated conditions were performed by four surface treatments, namely thermal oxidation, substrate overheating, exposition to glow discharge, and metal coating due to arc plasma. In the next step, the samples were regenerated on the same substrates with identical deposition technique. Damaging and re-growth of GPN samples were systematically characterized by scanning electron microscopy and Raman spectroscopy. The full regeneration of the structural and morphological properties of the samples has proven that this healing method by arc plasma is adequate for restoring the functionality of 2D nanostructures exposed to harsh environments.

Keywords： graphene platelet networks anodic arc discharge plasma healing scanning electron microscopy Raman spectroscopy

HTML PDF Collect

Engineering platelet-mimicking drug delivery vehicles

Quanyin Hu, Hunter N. Bomba, Zhen Gu

Frontiers of Chemical Science and Engineering 2017, Volume 11, Issue 4, Pages 624-632 doi: 10.1007/s11705-017-1614-6

Abstract: Platelets dynamically participate in various physiological processes, including wound repair, bacterialRecreating the specific biological features of platelets by mimicking the structure of the platelet or

Keywords： drug delivery platelets nanomedicine bio-inspired biomimetic

HTML PDF Collect

Platelet membrane-based and tumor-associated platelet- targeted drug delivery systems for cancer therapy

Yinlong Zhang, Guangna Liu, Jingyan Wei, Guangjun Nie

Frontiers of Medicine 2018, Volume 12, Issue 6, Pages 667-677 doi: 10.1007/s11684-017-0583-y

Abstract: Platelets have long been known to play critical roles in hemostasis by clumping and clotting blood vesselRecent experimental evidence strongly indicates that platelets can also interact with tumor cells byFor example, platelets have been shown to protect circulating cancer cells in blood circulation and toIn-depth understanding of the role of platelets in cancer progression and metastasis provides promisingprogresses in platelet membrane-based drug delivery and unique strategies that target tumor-associated platelets

Keywords： platelet-mimicking delivery systems tumor-associated platelets cancer therapy EPR effect