Search | Engineering

Subscribe Submit

Home Journals Focus Achievement Fronts About Us 中文版

Resource Type

Journal Article 8

Year

2021 1

2017 1

2016 1

2014 1

2013 1

2012 1

2011 1

2009 1

open ︾

Keywords

microRNA 5

Musa balbisiana 1

Liver 1

MicroRNAs 1

Muscle 1

Nerve 1

Noncoding RNAs 1

Skin 1

Tissue engineering 1

Vascular system 1

adipocyte 1

adipogenesis 1

antagomirs 1

biomarkers 1

cardiovascular disease 1

cold stress 1

differentiation 1

hepatitis B virus 1

hepatitis C virus 1

lung biology 1

open ︾

Search scope:

排序： Display mode:

The role of microRNAs in adipocyte differentiation

Rong Zhang, Di Wang, Zhuying Xia, Chao Chen, Peng Cheng, Hui Xie, Xianghang Luo

Frontiers of Medicine 2013, Volume 7, Issue 2, Pages 223-230 doi: 10.1007/s11684-013-0252-8

Abstract: is growing evidence indicating that a class of small non-coding single-stranded RNAs known as “microRNAs

Keywords： microRNA adipocyte differentiation adipogenesis

HTML PDF Collect

Cold stress responsive microRNAs and their targets in

Jingyi WANG,Juhua LIU,Caihong JIA,Hongxia MIAO,Jianbin ZHANG,Zhuo WANG,Biyu XU,Zhiqiang JIN

Frontiers of Agricultural Science and Engineering 2016, Volume 3, Issue 4, Pages 335-345 doi: 10.15302/J-FASE-2016121

Abstract: Recently, microRNAs (miRNAs) have been found to be involved in several plant processes such as growth

Keywords： cold stress microRNA Musa balbisiana

HTML PDF Collect

Circulating microRNAs in cardiovascular diseases: from biomarkers to therapeutic targets

Feng Wang,Chen Chen,Daowen Wang

Frontiers of Medicine 2014, Volume 8, Issue 4, Pages 404-418 doi: 10.1007/s11684-014-0379-2

Abstract:

microRNAs (miRNAs) are a class of conserved, short, non-coding RNAs that have important and potent

Keywords： microRNA cardiovascular disease biomarkers therapeutic target

HTML PDF Collect

MicroRNAs and lung cancers: from pathogenesis to clinical implications

Ji Qi, David Mu

Frontiers of Medicine 2012, Volume 6, Issue 2, Pages 134-155 doi: 10.1007/s11684-012-0188-4

Abstract: Here we summarize the functions of small-RNA-based, posttranscriptional gene regulators, i.e. microRNAsWe discuss the microRNAs that play oncogenic as well as tumor suppressive roles.We also touch on the value of microRNAs as markers for diagnosis, prognosis and the promising field of

Keywords： lung biology lung cancer microRNA

HTML PDF Collect

MicroRNAs and their roles in osteoclast differentiation

Zhuying Xia, Chao Chen, Peng Chen, Hui Xie, Xianghang Luo

Frontiers of Medicine 2011, Volume 5, Issue 4, Pages 414-419 doi: 10.1007/s11684-011-0168-0

Abstract: Limited evidence indicates that a class of small non-coding single-stranded RNAs known as “microRNAs”

Keywords： miRNA osteoclast differentiation antagomirs

HTML PDF Collect

MicroRNAs and hepatitis viruses

Gang LI MD , Xiaojia XIONG MM ,

Frontiers of Medicine 2009, Volume 3, Issue 3, Pages 265-270 doi: 10.1007/s11684-009-0055-0

Abstract: MicroRNAs (miRNAs) are a class of small RNA molecules.

Keywords： microRNA hepatitis B virus hepatitis C virus

HTML PDF Collect

Loss of monocarboxylate transporter 1 aggravates white matter injury after experimental subarachnoid hemorrhage in rats

Frontiers of Medicine 2021, Volume 15, Issue 6, Pages 887-902 doi: 10.1007/s11684-021-0879-9

Abstract: Monocarboxylic acid transporter 1 (MCT1) maintains axonal function by transferring lactic acid from oligodendrocytes to axons. Subarachnoid hemorrhage (SAH) induces white matter injury, but the involvement of MCT1 is unclear. In this study, the SAH model of adult male Sprague-Dawley rats was used to explore the role of MCT1 in white matter injury after SAH. At 48 h after SAH, oligodendrocyte MCT1 was significantly reduced, and the exogenous overexpression of MCT1 significantly improved white matter integrity and long-term cognitive function. Motor training after SAH significantly increased the number of ITPR2⁺SOX10⁺ oligodendrocytes and upregulated the level of MCT1, which was positively correlated with the behavioral ability of rats. In addition, miR-29b and miR-124 levels were significantly increased in SAH rats compared with non-SAH rats. Further intervention experiments showed that miR-29b and miR-124 could negatively regulate the level of MCT1. This study confirmed that the loss of MCT1 may be one of the mechanisms of white matter damage after SAH and may be caused by the negative regulation of miR-29b and miR-124. MCT1 may be involved in the neurological improvement of rehabilitation training after SAH.

Keywords： microRNAs monocarboxylate transporter 1 motor training subarachnoid hemorrhage white matter injury

HTML PDF Collect

Noncoding RNAs and Their Potential Therapeutic Applications in Tissue Engineering

Shiying Li, Tianmei Qian, Xinghui Wang, Jie Liu, Xiaosong Gu

Engineering 2017, Volume 3, Issue 1, Pages 3-15 doi: 10.1016/J.ENG.2017.01.005

Abstract:

Tissue engineering is a relatively new but rapidly developing field in the medical sciences. Noncoding RNAs (ncRNAs) are functional RNA molecules without a protein-coding function; they can regulate cellular behavior and change the biological milieu of the tissue. The application of ncRNAs in tissue engineering is starting to attract increasing attention as a means of resolving a large number of unmet healthcare needs, although ncRNA-based approaches have not yet entered clinical practice. In-depth research on the regulation and delivery of ncRNAs may improve their application in tissue engineering. The aim of this review is: to outline essential ncRNAs that are related to tissue engineering for the repair and regeneration of nerve, skin, liver, vascular system, and muscle tissue; to discuss their regulation and delivery; and to anticipate their potential therapeutic applications.

Keywords： Tissue engineering Noncoding RNAs MicroRNAs Nerve Skin Liver Vascular system Muscle