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Journal Article 5

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2017 1

2011 1

2009 2

Keywords

2-acetylpyrazine 1

b-amino ketone 1

Hb response 1

IMF 1

One–pot synthesis 1

agglomerated 1

anemia 1

c-Fos 1

catalysis 1

char sulfonic acid 1

coating 1

crystallization 1

early response 1

ferric carboxymaltose 1

ibuprofen tablets 1

inner-layer 1

intravenous iron 1

iron deficiency 1

iron sucrose 1

moisture migration 1

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randomized, controlled, open label non-inferiority trial of intravenous ferric carboxymaltose versus iron sucrose

Frontiers of Medicine doi: 10.1007/s11684-023-1001-2

Abstract: Although iron sucrose (IS) treatment is well-established in the country, ferric carboxymaltose (FCM)

Keywords： iron deficiency     anemia     intravenous iron     ferric carboxymaltose     iron sucrose     Hb response     early response    

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c-Fos expression in rat brainstem following intake of sucrose or saccharin

Ke Chen, Jianqun Yan, Jinrong Li, Bo Lv, Xiaolin Zhao

Frontiers of Medicine 2011, Volume 5, Issue 3,   Pages 294-301 doi: 10.1007/s11684-011-0144-8

Abstract: the solitary tract (NST) and parabrachial nucleus (PBN) of brainstem following ingestion of 0.25 M sucroseIntake of sucrose increased the number of FLI neurons in almost every subnucleus of the PBN (F = 7.610modulation of sweet tastant intake, but the significantly enhanced intensity of Fos expression induced by sucrose

Keywords： c-Fos     parabrachial     the nucleus of the solitary tract     sweet tastant     rat    

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Effects of sucrose crystallization and moisture migration on the structural changes of a coated intermediate

Tiancheng LI, Peng ZHOU, Theodore P. LABUZA

Frontiers of Chemical Science and Engineering 2009, Volume 3, Issue 4,   Pages 346-350 doi: 10.1007/s11705-009-0256-8

Abstract: water activity in different physical domains of samples during storage, while the crystallization of sucroseOur results suggested that both moisture loss and sucrose crystallization were mainly responsible forformation of the crusty intermediate inner layer, and the agglomerated matrix particles were the result of sucrose

Keywords： inner-layer     agglomerated     IMF     moisture migration     crystallization    

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One-pot three-component Mannich reaction catalyzed by sucrose char sulfonic acid

Qiong XU, Zhigao YANG, Dulin YIN, Jihui WANG

Frontiers of Chemical Science and Engineering 2009, Volume 3, Issue 2,   Pages 201-205 doi: 10.1007/s11705-009-0052-5

Abstract: Sucrose char sulfonic acid efficiently catalyzed the one-pot three-component Mannich reaction of ketones

Keywords： One–pot synthesis     b-amino ketone     char sulfonic acid     2-acetylpyrazine     catalysis    

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The feasibility of coating by cooling crystallization on ibuprofen naked tablets

Fatima Mameri, Ouahiba Koutchoukali, Mohamed Bouhelassa, Anne Hartwig, Leila Nemdili, Joachim Ulrich

Frontiers of Chemical Science and Engineering 2017, Volume 11, Issue 2,   Pages 211-219 doi: 10.1007/s11705-017-1619-1

Abstract: Sugar spray coating is a frequently used process in the pharmaceutical industry. However, this process presents the disadvantage to form an amorphous coating around the active ingredient. A crystalline coating formed on the surface of a tablet is highly desirable. Recently, a new process of coating by cooling crystallization has been developed and applied on bisacodyl pastilles obtained by melt crystallization. In this work, we investigated the feasibility of coating by cooling crystallization on ibuprofen “naked tablets” manufactured by compression. In the first part of this work, the solubility and the metastable zone width have been determined experimentally for the coating solution because they are essential factors for any crystallization process. In the second part, the coating process is investigated on the operating conditions that affect the surface morphology and the crystal growth rate. These experimental conditions include concentration of the coating solution, degree of sub-cooling, agitation speed, retention time, and surface properties of the naked ibuprofen tablets. The results show that naked tablet coating by cooling crystallization is feasible and can be applied in the pharmaceutical industry.

Keywords： coating     solution crystallization     ibuprofen tablets     sucrose    

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Title Author Date Type Operation

randomized, controlled, open label non-inferiority trial of intravenous ferric carboxymaltose versus iron sucrose

Journal Article

c-Fos expression in rat brainstem following intake of sucrose or saccharin

Ke Chen, Jianqun Yan, Jinrong Li, Bo Lv, Xiaolin Zhao

Journal Article

Effects of sucrose crystallization and moisture migration on the structural changes of a coated intermediate

Tiancheng LI, Peng ZHOU, Theodore P. LABUZA

Journal Article

One-pot three-component Mannich reaction catalyzed by sucrose char sulfonic acid

Qiong XU, Zhigao YANG, Dulin YIN, Jihui WANG

Journal Article

The feasibility of coating by cooling crystallization on ibuprofen naked tablets

Fatima Mameri, Ouahiba Koutchoukali, Mohamed Bouhelassa, Anne Hartwig, Leila Nemdili, Joachim Ulrich

Journal Article