The internal combustion engine (ICE) is an attractive power source for automobiles, with its superior storability, transportability, and suppliability of liquid fuel with high energy density. Compact ICEs with high performance and a low environmental load are greatly needed. In the future, smart active control of combustion by means of fuel spray injection must be considered as a breakthrough technology to address serious issues related to conventional ICEs, such as emissions. A designed fuel injection rate and spray pattern during the injection period have been technically developed, and combustion can be partially controlled in the conventional ICE. However, spatial fuel distribution is not progressing as desired in the field of combustion; thus, new and effective active control technologies for fuel spray are very necessary for the smart control of combustion. Cavitation, flash boiling, spray-to-spray interaction, spray-to-wall interaction, and air flow have potential as a basis for active attitude control of fuel spray. This article uses evidence from the literature to discuss the possibility of active spray attitude control for future fuel spray combustion technology in a smart compact ICE.