
The Anticancer Potential of Quassinoids-A Mini-Review
Cai Lu, Si-Nan Lu, Di Di, Wei-Wei Tao, Lu Fan, Jin-Ao Duan, Ming Zhao, Chun-Tao Che
Engineering ›› 2024, Vol. 38 ›› Issue (7) : 27-38.
The Anticancer Potential of Quassinoids-A Mini-Review
The anticancer potential of quassinoids has attracted a great deal of attention for decades, and scientific data revealing their possible applications in cancer management are continuously increasing in the literature. Aside from the potent cytotoxic and antitumor properties of these degraded triterpenes, several quassinoids have exhibited synergistic effects with anticancer drugs. This article provides an overview of the potential anticancer properties of quassinoids, including their cytotoxic and antitumor activities, mechanisms of action, safety evaluation, and potential benefits in combination with anticancer drugs.
Quassinoid / Anticancer potential / Antiproliferative mechanism / Safety evaluation / Synergistical combination with anticancer / drugs
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