CGMP Consortium: A Multicenter, Longitudinal Clinical Trial Plan for Constipation Multi-Omics and Precision Micro-Ecological Intervention Strategies

Engineering ›› 2024, Vol. 43 ›› Issue (12) : 17 -21. DOI: 10.1016/j.eng.2024.11.011

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Abstract

Highlights

• Prospective multi-omics, multicenter, longitudinal clinical trial protocol CGMP top-level design.

• The CGMP cohort will serve as a unique resource for studying the etiology of constipation and diagnosing constipation based on gut microbiota.

• The CGMP cohort study will help develop microbiota-targeted dietary or clinical therapies for various types of constipation.

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Linlin Wang, Tong Zhang, Hongliang Tian, Qiyi Chen, Lianmin Chen, Yuzheng Xue, Gaojue Wu, Yurong Tang, Ning Li, Qixiao Zhai, Wei Chen. CGMP Consortium: A Multicenter, Longitudinal Clinical Trial Plan for Constipation Multi-Omics and Precision Micro-Ecological Intervention Strategies. Engineering, 2024, 43(12): 17-21 DOI:10.1016/j.eng.2024.11.011