Plant Terpenoid Diversity: From Pathway Elucidation to Ecological Functions

Xiaochen Wang; Guodong Wang

doi:10.1016/j.eng.2025.11.021

Engineering ›› :202511021 DOI: 10.1016/j.eng.2025.11.021

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Plant Terpenoid Diversity: From Pathway Elucidation to Ecological Functions

Xiaochen Wang ^a
, Guodong Wang ^a^,^b^,^*

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Abstract

Terpenoids are the most diverse class of specialized metabolites in plants, despite being derived from two simple precursors, isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Terpene biosynthesis can be broadly divided into two stages: the formation of upstream carbon-hydrogen scaffolds and the downstream modification of these scaffolds. In this review, we first highlight recent advances in the biosynthesis of the upstream carbon-hydrogen backbones. We then discuss the techniques and methodologies used to elucidate the molecular details of the downstream modification reactions, particularly in the context of medicinal plants. Finally, we explore and forecast the future of biological function studies of plant terpenoids, with a specific focus on their roles in planta. This review aims to provide a comprehensive overview of current research trends and insights into terpene biosynthesis and their functional characterization in plants.

Keywords

Plant terpenoid / Multi-omics / Biosynthesis / Functional characterization

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Xiaochen Wang, Guodong Wang. Plant Terpenoid Diversity: From Pathway Elucidation to Ecological Functions. Engineering 202511021 DOI:10.1016/j.eng.2025.11.021

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