One Thousand Herb Genomes: Advancing Plant Secondary Metabolism Research in the Post-Omics Era

De-Yu Xie

doi:10.1016/j.eng.2025.12.001

Engineering ›› :202512001 DOI: 10.1016/j.eng.2025.12.001

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One Thousand Herb Genomes: Advancing Plant Secondary Metabolism Research in the Post-Omics Era

De-Yu Xie ^*

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Abstract

Sequencing 1254 herbgenomes including 1210 medicinal plants and fungi and 44 medicinal animals is a state-of-the-art project that will be instrumental to understanding therapeutic mechanisms of diverse medicinal plants. Based on my expertise in omics and plant secondary metabolism, I highlighted the sig-nificance of over one thousand herbgenomes for elucidating biosynthesis of plant flavonoids, terpenoids, nitrogen-containing secondary metabolites, and metabolic networks in the post-omics era. Meanwhile, I concisely discuss the necessity of high-quality sequencing and genome assembly for understanding plant secondary metabolism. In conclusion, the completion of over one thousand herbgenomes will advance knowledge of plant secondary metabolism and accelerate the discovery of novel medicinal metabolites.

Keywords

Genomics / Genome / Omics / Medicinal Plants / Medicines

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De-Yu Xie. One Thousand Herb Genomes: Advancing Plant Secondary Metabolism Research in the Post-Omics Era. Engineering 202512001 DOI:10.1016/j.eng.2025.12.001

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