Biomedical Engineering, a research group that is part of the Thoraxcenter of the Erasmus Medical Center, has a long tradition of innovation in the “golden triangle” of academic engineers, clinical doctors, and industry. This tradition started in the early 70s with, for example, the development of echocar-diography- and catheter-based ultrasound imaging. The founder, Professor Nicolaas Bom, and his successor, Professor Antonius van der Steen, are both members of the Netherlands Academy of Technology and Innovation (AcTI). Heartbeat OCT is this research group’s latest development. It is a micromotor-based imaging catheter that can make crisp motion-artifact-free images of the coronary arteries. By using these imaging catheters, the catheter-based treatment of heart attack and chest pain can be guided, and its quality will be improved so that fewer people will have to be retreated. This development will have an enormous impact on health care and its concomitant costs.