Journal Home Online First Current Issue Archive For Authors Journal Information 中文版

Engineering >> 2018, Volume 4, Issue 6 doi: 10.1016/j.eng.2018.08.005

Development of a Wireless-Controlled LED Array for the Tunable Optogenetic Control of Cellular Activities

a Department of Biomedical Engineering, Key Laboratory for Biomedical Engineering of Ministry of Education, Zhejiang Provincial Key Laboratory of Cardio-Cerebral Vascular Detection Technology and Medicinal Effectiveness Appraisal, Zhejiang University, Hangzhou 310027, China 

b Department of Hepatobiliary and Pancreatic Surgery, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310009, China c Department of Medical Cell Biology, Uppsala Biomedical Centre, Uppsala University, Uppsala 75123, Sweden 

# These authors contributed equally to this work

Available online: 2018-08-28

Next Previous

SupplementaryMaterials

Figures

Fig.1

Fig.2

References

[ 1 ] Bugaj LJ, O’Donoghue GP, Lim WA. Interrogating cellular perception and decision making with optogenetic tools. J Cell Biol 2017;216(1):25–8. link1

[ 2 ] Olson EJ, Tabor JJ. Optogenetic characterization methods overcome key challenges in synthetic and systems biology. Nat Chem Biol 2014;10 (7):502–11. link1

[ 3 ] Kolar K, Weber W. Synthetic biological approaches to optogenetically control cell signaling. Curr Opin Biotechnol 2017;47:112–9. link1

[ 4 ] Xu Y, Melia TJ, Toomre DK. Using light to see and control membrane traffic. Curr Opin Chem Biol 2011;15(6):822–30. link1

[ 5 ] Boyden ES, Zhang F, Bamberg E, Nagel G, Deisseroth K. Millisecond-timescale, genetically targeted optical control of neural activity. Nat Neurosci 2005;8 (9):1263–8. link1

[ 6 ] Xu Y, Nan D, Fan J, Bogan JS, Toomre D. Optogenetic activation reveals distinct roles of PIP3 and Akt in adipocyte insulin action. J Cell Sci 2016;129 (10):2085–95. link1

[ 7 ] Shao J, Xue S, Yu G, Yu Y, Yang X, Bai Y, et al. Smartphone-controlled optogenetically engineered cells enable semiautomatic glucose homeostasis in diabetic mice. Sci Transl Med 2017;9(387):eaal2298. link1

[ 8 ] Idevall-Hagren O, Dickson EJ, Hille B, Toomre DK, De Camilli P. Optogenetic control of phosphoinositide metabolism. Proc Natl Acad Sci USA 2012;109(35): E2316–23. link1

[ 9 ] Kennedy MJ, Hughes RM, Peteya LA, Schwartz JW, Ehlers MD, Tucker CL. Rapid blue-light-mediated induction of protein interactions in living cells. Nat Methods 2010;7(12):973–5. link1

[10] Xie B, Nguyen PM, Gucˇek A, Thonig A, Barg S, Idevall-Hagren O. Plasma membrane phosphatidylinositol 4,5-bisphosphate regulates Ca2+-influx and insulin secretion from pancreatic b cells. Cell Chem Biol 2016;23(7):816–26. link1

[11] Li J, Wang Y, Chiu SL, Cline HT. Membrane targeted horseradish peroxidase as a marker for correlative fluorescence and electron microscopy studies. Front Neural Circuits 2010;4:6. link1

Related Research