Search scope:
排序: Display mode:
Introduction to the special issue on the 2012 EUCOMES European Conference on Mechanism Science
Marco CECCARELLI, Fernando VIADERO
Frontiers of Mechanical Engineering 2013, Volume 8, Issue 1, Pages 1-2 doi: 10.1007/s11465-013-0368-1
Yi QIAN
Frontiers of Environmental Science & Engineering 2012, Volume 6, Issue 1, Pages 1-1 doi: 10.1007/s11783-012-0398-7
Social insurance for occupational diseases
Hengjin Dong, Shengnan Duan, Yuan Wu, Jing Wang, Xujun Ye
Frontiers of Medicine 2012, Volume 6, Issue 2, Pages 221-223 doi: 10.1007/s11684-012-0187-5
Research on Statistical Accounting Methods for Ecological Civilization in China
Shi Qingyan and Zhou Jing
Strategic Study of CAE 2017, Volume 19, Issue 4, Pages 67-73 doi: 10.15302/J-SSCAE-2017.04.011
The fundamental work in ecological civilization construction begins with the creation of an accounting and statistical system that can provide reliable data support for the purpose of monitoring, evaluation, and decision-making. Although there are data on the resources and environment of China, they cannot be effectively integrated into a unified framework due to the lack of a top-level accounting and statistical framework of ecological civilization. Considering the actual demands of ecological civilization construction, this study analyzes the problems that exist in the accounting and statistical system of ecological civilization in China and constructs a statistical indicator system and an accounting framework of ecological civilization. Further, it gives suggestions for the improvement of the accounting and statistical system of ecological civilization in China.
Keywords: ecological civilization SEEA2012-CF statistical system accounting framework natural resources balance
MicroRNAs and lung cancers: from pathogenesis to clinical implications
Ji Qi, David Mu
Frontiers of Medicine 2012, Volume 6, Issue 2, Pages 134-155 doi: 10.1007/s11684-012-0188-4
Lung cancer is the leading cause of cancer-related deaths in the US and worldwide. Better understanding of the disease is warranted for improvement in clinical management. Here we summarize the functions of small-RNA-based, posttranscriptional gene regulators, i.e. microRNAs, in the pathogenesis of lung cancers. We discuss the microRNAs that play oncogenic as well as tumor suppressive roles. We also touch on the value of microRNAs as markers for diagnosis, prognosis and the promising field of microRNA-based novel therapies for lung cancers.
Keywords: lung biology lung cancer microRNA
Mechanisms and impacts of chromosomal translocations in cancers
Jing H. Wang
Frontiers of Medicine 2012, Volume 6, Issue 3, Pages 263-274 doi: 10.1007/s11684-012-0215-5
Chromosomal aberrations have been associated with cancer development since their discovery more than a hundred years ago. Chromosomal translocations, a type of particular structural changes involving heterologous chromosomes, have made a critical impact on diagnosis, prognosis and treatment of cancers. For example, the discovery of translocation between chromosomes 9 and 22 and the subsequent success of targeting the fusion product BCR-ABL transformed the therapy for chronic myelogenous leukemia. In the past few decades, tremendous progress has been achieved towards elucidating the mechanism causing chromosomal translocations. This review focuses on the basic mechanisms underlying the generation of chromosomal translocations. In particular, the contribution of frequency of DNA double strand breaks and spatial proximity of translocating loci is discussed.
Keywords: DNA double strand breaks chromosomal translocations genomic instability spatial proximity carcinogenesis
Individualized medicine, health medicine, and constitutional theory in Chinese medicine
Qi Wang
Frontiers of Medicine 2012, Volume 6, Issue 1, Pages 1-7 doi: 10.1007/s11684-012-0173-y
The patterns of modern science and changes in the medical model can result in the transformation of the current state of individualized and health medicines into being the primary trend in medical development. Chinese and Western medical systems are dissimilar in terms of value orientations, thinking style, and research directions because of their different historical and cultural backgrounds. Individualized treatment in modern medicine is mainly established based on individual genome information and the differences in mononucleotide polymorphi-sms. However, such treatment method is expensive, creates an uncertain genetic marker, and leads to different result interpretations, among other problems. The Chinese constitutional theory developed in the 1970s expresses the principle behind Chinese health medicine and individual treatment and provides the corresponding methods. The Chinese constitutional theory divides the constitution of the Chinese population into nine categories based on established classification criteria. It promotes the study of the relationship of each constitution to diseases and Chinese medicine preparation toward adjusting the constitution and preventing diseases. The theory also provides methods and tools for individualized treatment. Constitution identification shows the direction and provides the core technology for the evaluation of the health status. By combining the developments in modern biotechnology, new diagnostic techniques and treatment models of constitution-differentiation, disease-differentiation, and syndrome-differentiation can be established for the development of individualized Chinese medicine treatment and health medicine for the international medical community.
Keywords: individualized medicine health medicine constitutional theory in Chinese medicine
Jixian GONG, Nan DUAN, Xueming ZHAO
Frontiers of Chemical Science and Engineering 2012, Volume 6, Issue 2, Pages 174-178 doi: 10.1007/s11705-012-1276-3
Keywords: evolutionary engineering astaxanthin strain improvement
Special issue on the Asian Congress on Biotechnology 2011
Bang-Ce YE
Frontiers of Chemical Science and Engineering 2012, Volume 6, Issue 2, Pages 125-125 doi: 10.1007/s11705-012-1291-4
Treatability aspects of urban stormwater stressors
Anthony N. TAFURI, Richard FIELD
Frontiers of Environmental Science & Engineering 2012, Volume 6, Issue 5, Pages 631-637 doi: 10.1007/s11783-012-0420-0
Keywords: stormwater wet weather flow urban runoff
A thermodynamic study of the removal of HCl and H
Joseph LEE, Bo FENG
Frontiers of Chemical Science and Engineering 2012, Volume 6, Issue 1, Pages 67-83 doi: 10.1007/s11705-011-1162-4
Keywords: syngas cleaning sorbent desulfurization dechlorination
Pei MA, Dan ZHANG
Frontiers of Environmental Science & Engineering 2012, Volume 6, Issue 4, Pages 498-508 doi: 10.1007/s11783-012-0429-4
Keywords:
immobilization
I-Ming CHEN, Feng GAO
Frontiers of Mechanical Engineering 2012, Volume 7, Issue 2, Pages 99-99 doi: 10.1007/s11465-012-0319-2
A comprehensive information database (CID) of breast cancer patients in China
Shuai Li, Li Fu
Frontiers of Medicine 2012, Volume 6, Issue 2, Pages 212-216 doi: 10.1007/s11684-012-0185-7
Particle therapy for cancers: a new weapon in radiation therapy
Guo-Liang Jiang
Frontiers of Medicine 2012, Volume 6, Issue 2, Pages 165-172 doi: 10.1007/s11684-012-0196-4
Particle irradiation started to draw attention in the past decade and has now become a hotspot in the radiation oncology community. This article reviews the most advanced developments in particle irradiation, focusing on the characteristics of proton and carbon ions in radiation physics and radiobiology. The Bragg peak of physical dose distribution causes proton and carbon beams to optimally meet the requirement for cancer irradiation because the Bragg peak permits the accurate concentration of the dose on the tumor, thus sparing the adjacent normal tissues. Moreover, carbon ion has more radiobiological benefits than photon and proton beams. These benefits include stronger sterilization effects on intrinsic radio-resistant tumors and more effective killing of hypoxic, G0, and S phase cells. Compared with the most advanced radiation techniques using photon, such as three-dimensional conformal radiation therapy and intensity-modulated radiation therapy, proton therapy has yielded more promising outcomes in local control and survival for head and neck cancers, prostate carcinoma, and pediatric cancers. Carbon therapy in Japan showed even more promising results than proton therapy. The local controls and overall survivals were as good as that treated by surgery in early stages of non-small cell lung cancer, hepatocellular carcinoma, prostate carcinoma, and head and neck cancers, especially for such highly resistant tumors as melanoma. The non-invasive nature of particle therapy affords more patients with chances to receive and benefit from treatment. Particle therapy is gradually getting attention from the oncology community. However, the cost of particle therapy facilities has limited the worldwide use of this technology.
Keywords: radiation therapy particle therapy proton carbon cancer
Title Author Date Type Operation
Introduction to the special issue on the 2012 EUCOMES European Conference on Mechanism Science
Marco CECCARELLI, Fernando VIADERO
Journal Article
Social insurance for occupational diseases
Hengjin Dong, Shengnan Duan, Yuan Wu, Jing Wang, Xujun Ye
Journal Article
Research on Statistical Accounting Methods for Ecological Civilization in China
Shi Qingyan and Zhou Jing
Journal Article
MicroRNAs and lung cancers: from pathogenesis to clinical implications
Ji Qi, David Mu
Journal Article
Individualized medicine, health medicine, and constitutional theory in Chinese medicine
Qi Wang
Journal Article
Introduction to the special issue on the “IFToMM International Symposium on Robotics and Mechatronics”
I-Ming CHEN, Feng GAO
Journal Article
A comprehensive information database (CID) of breast cancer patients in China
Shuai Li, Li Fu
Journal Article