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Journal Article 1

Year

2013 1

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BCR/ABL 1

RAL 1

RAS 1

chronic myelogenous leukemia (CML) 1

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The role of RAS effectors in BCR/ABL induced chronic myelogenous leukemia

Jessica Fredericks, Ruibao Ren

Frontiers of Medicine 2013, Volume 7, Issue 4,   Pages 452-461 doi: 10.1007/s11684-013-0304-0

Abstract: this rescue effect, we utilize well-characterized RAS effector loop mutants and determine that the RALInhibition of this pathway by a dominant negative RAL is capable of delaying disease progression.Results from the present study support the notion of RAL inhibition as a potential therapy for BCR/ABL-induced

Keywords： BCR/ABL     chronic myelogenous leukemia (CML)     RAS     RAL    

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Title Author Date Type Operation

The role of RAS effectors in BCR/ABL induced chronic myelogenous leukemia

Jessica Fredericks, Ruibao Ren

Journal Article