2015年 第9卷 第1期
《医学前沿（英文）》 >> 2015年 第9卷 第1期 doi: 10.1007/s11684-014-0344-0
A ruptured recurrent small bowel gastrointestinal stromal tumour causing hemoperitoneum
1. Faculty of Medicine, The Chinese University of Hong Kong, Shatin, Hong Kong SAR, China.
2. Dr. K.M. Chung’s Clinic, Rm 807, Hang Seng Tsimshatsui Building, 18 Carnarvon Road, Tsimshatsui, Hong Kong SAR, China.
3. Department of Surgery, Pamela Youde Nethersole Eastern Hospital, Hong Kong SAR, China.
4. Department of Surgery, Queen Elizabeth Hospital, Hong Kong SAR, China
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摘要
Hemoperitoneum is a rare and potentially life-threatening complication of GIST. We reported a 54-year-old man who developed disseminated intra-abdominal recurrence from a previously resected gastrointestinal stromal tumour (GIST) of the small bowel, and the patient presented with hemoperitoneum. Emergent debulking surgery was performed. A high dose imatinib was prescribed. Despite the presence of residual disease, the patient was well clinically 8 months after the operation. Even though, there is no evidence to support the routine use of debulking surgery in the management of GIST. In our patient, disease progression after second line targeted therapy and the absence of alternative treatment options for spontaneous rupture and hemoperitoneum prompted us to treat the patient aggressively. Resection of the ruptured GIST was carried out for control of bleeding and to prevent recurrent bleeding in this patient with good surgical risks. During the treatment decision-making, the patient’s general condition, the risk of surgery and the extent of dissemination were taken into consideration. In this patient who presented with spontaneous rupture of a small intestinal GIST, the novel use of targeted therapy and aggressive surgical treatment produced reasonably good survival outcome.
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