Blasting engineering in complex urban environments is considered to influence the safety and stability of the overlying drainage box culvert structure owing to vibration. Therefore, field blasting and vibration tests were performed on the blasting engineering of the Wuhan Metro Line 8 connected aisle, and the LS-DYNA software was used to analyze the dynamic response characteristics of an underground drainage box culvert during the blasting test. The vibration response evolution law of the buried drainage box culvert under blasting vibration was investigated, and a safe surface control standard for the blast vibration of a drainage box culvert is proposed. The results reveal that the maximum tensile stress of the box culvert structure was 0.33 MPa. The peak particle velocity (PPV) and peak tensile stress (PTS) of the drainage box culvert decreased as the water level in the box culvert increased. Based on the relationship between the tensile stress of the box culvert, PPV of the box culvert, and PPV of the surface, it is proposed that the surface control velocity of the buried drainage box culvert is 1.36 cm/s.