Owing to advancement in advanced manufacturing technology, the reinforcement design of concrete structures has become an important topic in structural engineering. Based on bi-directional evolutionary structural optimization (BESO), a new approach is developed in this study to optimize the reinforcement layout in steel-reinforced concrete (SRC) structures. This approach combines a minimum compliance objective function with a hybrid truss-continuum model. Furthermore, a modified bi-directional evolutionary structural optimization (M-BESO) method is proposed to control the level of tensile stress in concrete. To fully utilize the tensile strength of steel and the compressive strength of concrete, the optimization sensitivity of steel in a concrete–steel composite is integrated with the average normal stress of a neighboring concrete. To demonstrate the effectiveness of the proposed procedures, reinforcement layout optimizations of a simply supported beam, a corbel, and a wall with a window are conducted. Clear steel trajectories of SRC structures can be obtained using both methods. The area of ​​critical tensile stress in concrete yielded by the M-BESO is more than 40% lower than that yielded by the uniform design and BESO. Hence, the M-BESO facilitates a fully digital workflow that can be extremely effective for improving the design of steel reinforcements in concrete structures.