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Diagnostic evaluation of plasma aldosterone concentration to plasma renin activity ratio in primary aldosteronism

ZHANG Huilan, WANG Daowen

《医学前沿（英文）》 2008年 第2卷 第1期   页码 11-14 doi: 10.1007/s11684-008-0003-4

摘要： Using the plasma aldosterone concentration to plasma renin activity ratio (PAC/PRA ratio) as the screening test of choice for primary aldosteronism in hypertensive patients, we studied the clinical characteristics and the diagnostic value of PAC/PRA ratio in primary aldosteronism. The plasma aldosterone concentration (PAC) and plasma renin activity (PRA) levels were measured by radioimmunoassay in 902 hypertensive patients from out-patient clinics or hospitals. One hundred and twenty-six suspected primary aldosteronism patients whose PAC/PRA ratio was > 25 ng/dL/ng/mL/hr had a lamellar computed tomography (CT) scan in the adrenal gland and follow-up visits. The proportion of primary aldosteronism in hypertensive patients was 14% (126/902). There were 54 patients with unilateral or bilateral hyperplasia and 25 patients with adenoma according to the CT scan. 39% (49/126) of the patients with primary aldosteronism had hypokalemia. Twenty-five patients received surgical treatment. The efficacy and cure rates were 100% (25/25) and 48% (12/25), respectively. The effective rate of aldactone and the single-drug cure rate were 89% (48/54) and 24% (13/54), respectively. Primary aldosteronism affects over 10% of hypertensive patients in China. The PAC/PRA ratio can be considered as a routine screening test in hypertensives, especially resistant hypertensive patients and a high PAC/PRA ratio is an invaluable index in primary aldosteronism diagnosis.
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Important parameters in plasma jets for the production of RONS in liquids for plasma medicine: A brief

Anna Khlyustova, Cédric Labay, Zdenko Machala, Maria-Pau Ginebra, Cristina Canal

《化学科学与工程前沿（英文）》 2019年 第13卷 第2期   页码 238-252 doi: 10.1007/s11705-019-1801-8

摘要： Reactive oxygen and nitrogen species (RONS) are among the key factors in plasma medicine. They are generated by atmospheric plasmas in biological fluids, living tissues and in a variety of liquids. This ability of plasmas to create a delicate mix of RONS in liquids has been used to design remote or indirect treatments for oncological therapy by treating biological fluids by plasmas and putting them in contact with the tumour. Documented effects include selective cancer cell toxicity, even though the exact mechanisms involved are still under investigation. However, the “right” dose for suitable therapeutical activity is crucial and still under debate. The wide variety of plasma sources hampers comparisons. This review focuses on atmospheric pressure plasma jets as the most studied plasma devices in plasma medicine and compiles the conditions employed to generate RONS in relevant liquids and the concentration ranges obtained. The concentrations of H O , NO , NO and short-lived oxygen species are compared critically to provide a useful overview for the reader.

关键词： atmospheric plasma jets     liquids     ROS     RNS     plasma-dose    

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Kinetic Monte Carlo simulations of plasma-surface reactions on heterogeneous surfaces

Daniil Marinov

《化学科学与工程前沿（英文）》 2019年 第13卷 第4期   页码 815-822 doi: 10.1007/s11705-019-1837-9

摘要： Reactions of atoms and molecules on chamber walls in contact with low temperature plasmas are important in various technological applications. Plasma-surface interactions are complex and relatively poorly understood. Experiments performed over the last decade by several groups prove that interactions of reactive species with relevant plasma-facing materials are characterized by distributions of adsorption energy and reactivity. In this paper, we develop a kinetic Monte Carlo (KMC) model that can effectively handle chemical kinetics on such heterogenous surfaces. Using this model, we analyse published adsorption-desorption kinetics of chlorine molecules and recombination of oxygen atoms on rotating substrates as a test case for the KMC model.

关键词： plasma-surface interaction     kinetic Monte Carlo     plasma nano technology    

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From plasma to plasmonics: toward sustainable and clean water production through membranes

《化学科学与工程前沿（英文）》 2023年 第17卷 第12期   页码 1809-1836 doi: 10.1007/s11705-023-2339-3

摘要： The increasing demand for potable water is never-ending. Freshwater resources are scarce and stress is accumulating on other alternatives. Therefore, new technologies and novel optimization methods are developed for the existing processes. Membrane-based processes are among the most efficient methods for water treatment. Yet, membranes suffer from severe operational problems, namely fouling and temperature polarization. These effects can harm the membrane’s permeability, permeate recovery, and lifetime. To mitigate such effects, membranes can be treated through two techniques: plasma treatment (a surface modification technique), and treatment through the use of plasmonic materials (surface and bulk modification). This article showcases plasma- and plasmonic-based treatments in the context of water desalination/purification. It aims to offer a comprehensive review of the current developments in membrane-based water treatment technologies along with suggested directions to enhance its overall efficiency through careful selection of material and system design. Moreover, basic guidelines and strategies are outlined on the different membrane modification techniques to evaluate its prerequisites. Besides, we discuss the challenges and future developments about these membrane modification methods.

关键词： water treatment     membrane-based process     plasma treatment     plasma polymerization     plasmonic     light-to-heat conversion    

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Atomistic simulations of plasma catalytic processes

Erik C. Neyts

《化学科学与工程前沿（英文）》 2018年 第12卷 第1期   页码 145-154 doi: 10.1007/s11705-017-1674-7

摘要： There is currently a growing interest in the realisation and optimization of hybrid plasma/catalyst systems for a multitude of applications, ranging from nanotechnology to environmental chemistry. In spite of this interest, there is, however, a lack in fundamental understanding of the underlying processes in such systems. While a lot of experimental research is already being carried out to gain this understanding, only recently the first simulations have appeared in the literature. In this contribution, an overview is presented on atomic scale simulations of plasma catalytic processes as carried out in our group. In particular, this contribution focusses on plasma-assisted catalyzed carbon nanostructure growth, and plasma catalysis for greenhouse gas conversion. Attention is paid to what can routinely be done, and where challenges persist.

关键词： atomic scale simulation     plasma-catalyst    

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Plasma-catalysis: Is it just a question of scale?

J. Christopher Whitehead

《化学科学与工程前沿（英文）》 2019年 第13卷 第2期   页码 264-273 doi: 10.1007/s11705-019-1794-3

摘要： The issues of describing and understanding the changes in performance that result when a catalyst is placed into plasma are discussed. The different chemical and physical interactions that result and how their combination might produce beneficial results for the plasma-catalytic processing of different gas streams are outlined with particular emphasis being placed on the different range of spatial and temporal scales that must be considered both in experiment and modelling. The focus is on non-thermal plasma where the lack of thermal equilibrium creates a range of temperature scales that must be considered. This contributes in part to a wide range of inhomogeneity in different properties such as species concentrations and electric fields that must be determined experimentally by methods and be incorporated into modelling. It is concluded that plasma-catalysis is best regarded as conventional catalysis perturbed by the presence of a discharge, which modifies its operating conditions, properties and outcomes often in a very localised way. The sometimes used description “plasma-activated catalysis” is an apt one.

关键词： plasma catalysis     plasma-activated catalysis     non-thermal plasma     CO2 conversion    

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Submerged arc plasma system combined with ozone oxidation for the treatment of wastewater containing

《环境科学与工程前沿（英文）》 2021年 第15卷 第5期 doi: 10.1007/s11783-020-1384-0

摘要：

• Submerged arc plasma was introduced in terms of wastewater treatment.

关键词： Thermal plasma     Submerged arc plasma     Wastewater     Ozone     Phenol     Highly energetic electron    

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Modelling and diagnostics of multiple cathodes plasma torch system for plasma spraying

Kirsten BOBZIN, Nazlim BAGCIVAN, Lidong ZHAO, Ivica PETKOVIC, Jochen SCHEIN, Karsten HARTZ-BEHREND, Stefan KIRNER, José-Luis MARQUéS, Günter FORSTER

《机械工程前沿（英文）》 2011年 第6卷 第3期   页码 324-331 doi: 10.1007/s11465-011-0125-2

摘要：

Usage of a multiple-arcs system has significantly improved process stability and coating properties in air plasma spraying. However, there are still demands on understanding and controlling the physical process to determine process conditions for reproducible coating quality and homogeneity of coating microstructure. The main goal of this work is the application of numerical simulation for the prediction of the temperature profiles at the torch outlet for real process conditions. Behaviour of the gas flow and electric arcs were described in a three-dimensional numerical model. The calculated results showed the characteristic triangular temperature distribution at the torch nozzle outlet caused by three electric arcs. These results were compared with experimentally determined temperature distributions, which were obtained with specially developed computed tomography equipment for reconstructing the emissivity and temperature distribution of the plasma jet close to the torch exit. The calculated results related to temperature values and contours were verified for the most process parameters with experimental ones.

关键词： plasma spraying     electric arc     three-cathode plasma torch     numerical simulation     computed tomography    

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Gender differences in the relationship between plasma lipids and fasting plasma glucose in non-diabetic

null

《医学前沿（英文）》 2014年 第8卷 第4期   页码 477-483 doi: 10.1007/s11684-014-0346-y

摘要：

The association between dyslipidemia and elevated fasting glucose in type 2 diabetes is well known. In non-diabetes, whether this association still exists, and whether dyslipidemia is an independent risk factor for high fasting plasma glucose (FPG) levels are not clear. This cross-sectional study recruited 3460 non-diabetic Chinese subjects (1027 men, and 2433 women, aged 35–75 years old) who participated in a health survey. Men and women were classified into tertiles by levels of plasma lipids respectively. In women, the prevalence of impaired fasting glucose (IFG) was decreased with increased HDL-C. A stepwise increase in HDL-C was associated with decreasing FPG levels (lowest tertiles, FPG: 5.376±0.018; middle tertiles, 5.324±0.018; highest tertiles, 5.276±0.018 mmol/L; P=0.001). Reversely, FPG levels increased from lowest tertiles to highest tertiles of LDL-C, TC, and TG. we found that women in the first tertile with lower HDL-C level had a 1.75-fold increase in risk of IFG compared with non-diabetic women in the third tertile with higher HDL-C level (OR: 1.75; 95% CI: 1.20--2.56). In men, no significant association was found. We took age, BMI, waist/hip ratio, education, smoking, alcohol drinking, and physical exercise as adjusted variables. In Chinese non-diabetic women, dyslipidemia is independently associated with high levels of FPG; TG, HDL-C, and LDL-C are predictors of IFG independent of BMI and waist/hip ratio.

关键词： dyslipidemia     plasma lipids     plasma fasting glucose     impaired fasting glucose     non-diabetes    

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Cross-sectional network analysis of plasma proteins/metabolites correlated with pathogenesis and therapeutic

《医学前沿（英文）》 doi: 10.1007/s11684-023-1022-x

摘要： The treatment of PML/RARA+ acute promyelocytic leukemia (APL) with all-trans-retinoic acid and arsenic trioxide (ATRA/ATO) has been recognized as a model for translational medicine research. Though an altered microenvironment is a general cancer hallmark, how APL blasts shape their plasma composition is poorly understood. Here, we reported a cross-sectional correlation network to interpret multilayered datasets on clinical parameters, proteomes, and metabolomes of paired plasma samples from patients with APL before or after ATRA/ATO induction therapy. Our study revealed the two prominent features of the APL plasma, suggesting a possible involvement of APL blasts in modulating plasma composition. One was characterized by altered secretory protein and metabolite profiles correlating with heightened proliferation and energy consumption in APL blasts, and the other featured APL plasma-enriched proteins or enzymes catalyzing plasma-altered metabolites that were potential trans-regulatory targets of PML/RARA. Furthermore, results indicated heightened interferon-gamma signaling characterizing a tumor-suppressing function of the immune system at the first hematological complete remission stage, which likely resulted from therapy-induced cell death or senescence and ensuing supraphysiological levels of intracellular proteins. Overall, our work sheds new light on the pathophysiology and treatment of APL and provides an information-rich reference data cohort for the exploratory and translational study of leukemia microenvironment.

关键词： acute promyelocytic leukemia     plasma proteomics     plasma metabolomics     cross-sectional correlation network     pathogenesis     treatment    

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The role of ions in plasma catalytic carbon nanotube growth: A review

Erik C. Neyts

《化学科学与工程前沿（英文）》 2015年 第9卷 第2期   页码 154-162 doi: 10.1007/s11705-015-1515-5

摘要： While it is well-known that the plasma-enhanced catalytic chemical vapor deposition (PECVD) of carbon nanotubes (CNTs) offers a number of advantages over thermal CVD, the influence of the various individual contributing factors is not well understood. Especially the role of ions is unclear, since ions in plasmas are generally associated with sputtering rather than with growing a material. Even so, various studies have demonstrated the beneficial effects of ion bombardment during the growth of CNTs. This review looks at the role of the ions in plasma-enhanced CNT growth as deduced from both experimental and simulation studies. Specific attention is paid to the beneficial effects of ion bombardment. Based on the available literature, it can be concluded that ions can be either beneficial or detrimental for carbon nanotube growth, depending on the exact conditions and the control over the growth process.

关键词： plasma-enhanced chemical vapor deposition (PECVD)     carbon nanotube (CNT)     ion bombardment     defect healing    

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Sub-nanometer finishing of polycrystalline tin by inductively coupled plasma-assisted cutting

《机械工程前沿（英文）》 2023年 第18卷 第3期 doi: 10.1007/s11465-023-0751-5

摘要： Polycrystalline tin is an ideal excitation material for extreme ultraviolet light sources. However, the existence of grain boundary (GB) limits the surface roughness of polycrystalline tin after single-point diamond turning (SPDT). In this work, a novel method termed inductively coupled plasma (ICP)-assisted cutting was developed for the sub-nanometer finishing of polycrystalline tin. The relationship between ICP power, processing time, and modification depth was established by thermodynamic simulation, and the fitted heat transfer coefficient of polycrystalline tin was 540 W/(m2·K). The effects of large-thermal-gradient ICP treatment on the microstructure of polycrystalline tin were studied. After 0.9 kW ICP processing for 3.0 s, corresponding to the temperature gradient of 0.30 K/µm, the grain size of polycrystalline tin was expanded from a size of approximately 20–80 μm to a millimeter scale. The Taguchi method was used to investigate the effects of rotational speed, depth of cut, and feed rate on SPDT. Experiments conducted based on the ICP system indicated that the plasma-assisted cutting method promoted the reduction of the influence of GB steps on the finishing of polycrystalline tin, thereby achieving a surface finish from 8.53 to 0.80 nm in Sa. The results of residual stress release demonstrated that the residual stress of plasma-assisted turning processing after 504 h stress release was 10.7 MPa, while that of the turning process without the ICP treatment was 41.6 MPa.

关键词： plasma-assisted cutting     polycrystalline tin     single-point diamond turning     surface roughness    

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Power-to-chemicals: sustainable liquefaction of food waste with plasma-electrolysis

《化学科学与工程前沿（英文）》 2023年 第17卷 第5期   页码 594-605 doi: 10.1007/s11705-022-2255-y

摘要： The increasing amount of food waste from various industrial, agricultural, and household sources is an environmental burden if managed inappropriately. Numerous waste management approaches have been developed for the disposal of food waste, but still suffer from either high cost, production of toxic by-products, or secondary environmental pollutions. Herein, we report a new and sustainable plasma electrolysis biorefinery route for the rapid and efficient liquefaction of food waste. During the plasma electrolysis process, only the solvent is added to liquefy the waste, and anions in the waste can contribute to catalyzing the biowaste conversion. While liquefying the waste, the highly reactive species produced in the plasma electrolysis process can efficiently reduce the content of O, N, and Cl in the liquefied products and oxidize most of the metals into solid residues. Especially, the removal rate of Na and K elements was greater than 81%, which is significantly higher than using the traditional oil bath liquefaction, resulting in a relatively high-quality biocrude oil with a high heating value of 25.86 MJ·kg–1. Overall, this proposed strategy may provide a new sustainable and eco-friendly avenue for the power-to-chemicals valorization of food waste under benign conditions.

关键词： plasma electrolysis     food waste     liquefaction     resource recovery    

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Platelet-rich plasma: combinational treatment modalities for musculoskeletal conditions

null

《医学前沿（英文）》 2018年 第12卷 第2期   页码 139-152 doi: 10.1007/s11684-017-0551-6

摘要：

Current research on common musculoskeletal problems, including osteoarticular conditions, tendinopathies, and muscle injuries, focuses on regenerative translational medicine. Platelet-rich plasma therapies have emerged as a potential approach to enhance tissue repair and regeneration. Platelet-rich plasma application aims to provide supraphysiological concentrations of platelets and optionally leukocytes at injured/pathological tissues mimicking the initial stages of healing. However, the efficacy of platelet-rich plasma is controversial in chronic diseases because patients’ outcomes show partial improvements. Platelet-rich plasma can be customized to specific conditions by selecting the most appropriate formulation and timing for application or by combining platelet-rich plasma with synergistic or complementary treatments. To achieve this goal, researchers should identify and enhance the main mechanisms of healing. In this review, the interactions between platelet-rich plasma and healing mechanisms were addressed and research opportunities for customized treatment modalities were outlined. The development of combinational platelet-rich plasma treatments that can be used safely and effectively to manipulate healing mechanisms would be valuable and would provide insights into the processes involved in physiological healing and pathological failure.

关键词： regenerative medicine     joint conditions     muscle injuries     platelet rich plasma     tendinopathy     healing mechanisms    

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等离子表面冶金技术的现状与发展

徐重

《中国工程科学》 2002年 第4卷 第2期   页码 36-41

摘要：

双层辉光离子渗金属技术已成功地在普通碳钢表面形成高速钢、其中包括时效硬化高速钢、不锈钢以及镍基合金等；该技术已成功地应用于手用锯条和机用锯条，使其齿部形成高速钢，锯条不仅具有高速钢的切削性能，而且柔韧不断;钛合金表面经离子渗钼等工处理后，Ti6Al4V的耐磨性得到大幅度提高;经离子渗铌等工艺处理后，TiAl金属间化合物的抗高温氧化性能明显改善。

在双层辉光离子渗金属技术的基础上，又发展了加弧辉光离子渗金属，双辉钎焊技术，双阴极辉光放电超硬薄膜合成技术，以及陶瓷表面金属化和异性材料焊接技术等。

关键词： 等离子体     等离子表面冶金     双层辉光离子渗金属    

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标题 作者 时间 类型 操作

Diagnostic evaluation of plasma aldosterone concentration to plasma renin activity ratio in primary aldosteronism

ZHANG Huilan, WANG Daowen

期刊论文

Important parameters in plasma jets for the production of RONS in liquids for plasma medicine: A brief

Anna Khlyustova, Cédric Labay, Zdenko Machala, Maria-Pau Ginebra, Cristina Canal

期刊论文

Kinetic Monte Carlo simulations of plasma-surface reactions on heterogeneous surfaces

Daniil Marinov

期刊论文

From plasma to plasmonics: toward sustainable and clean water production through membranes

期刊论文

Atomistic simulations of plasma catalytic processes

Erik C. Neyts

期刊论文

Plasma-catalysis: Is it just a question of scale?

J. Christopher Whitehead

期刊论文

Submerged arc plasma system combined with ozone oxidation for the treatment of wastewater containing

期刊论文

Modelling and diagnostics of multiple cathodes plasma torch system for plasma spraying

Kirsten BOBZIN, Nazlim BAGCIVAN, Lidong ZHAO, Ivica PETKOVIC, Jochen SCHEIN, Karsten HARTZ-BEHREND, Stefan KIRNER, José-Luis MARQUéS, Günter FORSTER

期刊论文

Gender differences in the relationship between plasma lipids and fasting plasma glucose in non-diabetic

null

期刊论文

Cross-sectional network analysis of plasma proteins/metabolites correlated with pathogenesis and therapeutic

期刊论文

The role of ions in plasma catalytic carbon nanotube growth: A review

Erik C. Neyts

期刊论文

Sub-nanometer finishing of polycrystalline tin by inductively coupled plasma-assisted cutting

期刊论文

Power-to-chemicals: sustainable liquefaction of food waste with plasma-electrolysis

期刊论文

Platelet-rich plasma: combinational treatment modalities for musculoskeletal conditions

null

期刊论文

等离子表面冶金技术的现状与发展

徐重

期刊论文