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Hydrophilic modification of poly(aryl sulfone) membrane materials toward highly-efficient environmental

《化学科学与工程前沿（英文）》 2022年 第16卷 第5期   页码 614-633 doi: 10.1007/s11705-021-2115-1

摘要： Poly(aryl sulfone) as a typical membrane material has been widely used due to excellent mechanical, chemical and thermal stability. However, the inherent hydrophobicity of poly(aryl sulfone) based membranes bears with the fouling issue during applications, which makes the membrane tending to adsorb contaminants on the surface so as to result in decreased separation performance and lifetime. In this critical review, we give a comprehensive overview on characterizations of hydrophilic membrane and diverse hydrophilic modification approaches of poly(aryl sulfone) membranes, predominantly including bulky, blending and surface modification technology. The discussions on the different modification methods have been provided in-depth. Besides, focusing on modification methods and performance of modified membranes, the related mechanisms for the performance enhancement are discussed too. At last, the perspectives are provided to guide the future directions to develop novel technology to manipulate the hydrophilicity of poly(aryl sulfone) membranes toward diverse practical and multi-functional applications.

关键词： poly(aryl sulfone)     membrane separations     modification     hydrophilicity     water treatment    

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Effect of electrokinetic property of charged polyether sulfone membrane on bovine serum albumin fouling

Xiaorong Meng, Shanshan Huo, Lei Wang, Xudong Wang, Yongtao Lv, Weiting Tang, Rui Miao, Danxi Huang

《环境科学与工程前沿（英文）》 2017年 第11卷 第2期 doi: 10.1007/s11783-017-0907-9

摘要： Negatively charged CMPES and positively charged QAPES membranes were fabricated. Charge modification reduced the adhesion forces between PES UF membranes and BSA. QAPES-BSA / was weaker than that of CMPES-BSA at pH 3 and on the contrary at pH 9. Flux decline rate was positively correlated with the adhesion forces of membrane-BSA. Variation of adhesion was consistent with that of potential absolute values. Negatively charged carboxymethylated polyethersulfone (CMPES) and positively charged quaternized polyethersulfone (QAPES) ultrafiltration (UF) membranes were prepared by bulk chemical modification and non-solvent induced phase separation method. The effects of PES membrane interfacial electrokinetic property on the bovine serum albumin (BSA) membrane fouling behavior were studied with the aid of the membrane-modified colloidal atomic force microscopy (AFM) probe. Electrokinetic test results indicated that the streaming potential (D ) of QAPES membrane was not consistent with its expected value, however, within the pH range of 3–10, the potentials of two charged-modified PES membranes were more stable than the unmodified membrane. When pH value was 3, 4.7 or 9, the interaction behavior between charged PES membrane and BSA showed that there was significant linear correlation between the jump distance of membrane-BSA adhesion force ( ) and the potential absolute value. Charged modification significantly reduced the adhesion of PES membrane-BSA, and the adhesion data was good linear correlated with the flux decline rate in BSA filtration process, especially reflected in the CMPES membrane. The above experimental facts proved that the charged membrane interfacial electric double layer structure and its electrokinetic property had strong ties with the protein membrane fouling behavior.

关键词： Charged PES UF membrane     BSA     Electrokinetic characterization     Adhesion force     Jump distance    

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Synthesis, molecular docking and antibacterial evaluation of 2-(4-(4-aminophenylsulfonyl)phenylamino)-3-(thiophen-2-ylthio)naphthalene-1,4-dione derivatives

Palanisamy RAVICHANDIRAN, Dhanaraj PREMNATH, Samuel VASANTHKUMAR

《化学科学与工程前沿（英文）》 2015年 第9卷 第1期   页码 46-56 doi: 10.1007/s11705-015-1506-6

摘要： A new series of 2-(4-(4-aminophenylsulfonyl)phenylamino)-3-(thiophen-2-ylthio)naphthalene-1,4-dione derivatives ( 3a-3n) were synthesized and characterized by spectral techniques. To understand the interaction of binding sites with bacterial protein receptor, the docking study was performed by the GLIDE program and compound -(4-(4-(1,4-dioxo-3-(thiophen-2-ylthio)-1,4-dihydronaphthalen-2-ylamino)phenylsulfonyl)phenyl)-3-methylbenzamide ( 3b) exhibited good glide and E model scores of ?5.89 and ?94.90, respectively. Moreover among all the molecules studied including the standards used, namely Sparfloxacin (4.8 μg/mL) and Norfloxacin (no inhibition observed) for their antibacterial property, compound -(4-(4-(1,4-dioxo-3-(thiophen-2-ylthio)-1,4-dihydronaphthalen-2-ylamino)phenylsulfonyl)phenyl)-4-nitrobenzamide ( 3e) exhibited the lowest minimum inhibitory concentration (MIC) value of 1.3 μg/mL against .

关键词： MIC     2-thiophene thiol     water as solvent     acid chlorides     sulfone    

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含硫醚和砜亚结构的新型芳香酰胺类衍生物的设计、合成及生物活性 Article

华学文, 刘南南, 周沙, 张蕾蕾, 殷昊, 王桂清, 范志金, 马翼

《工程（英文）》 2020年 第6卷 第5期   页码 553-559 doi: 10.1016/j.eng.2019.09.011

摘要：

近年来，土壤线虫危害日趋严重，然而市场上应用的杀线虫剂品种匮乏且结构单一。氟吡菌酰胺（fluopyram）是德国拜耳公司开发的琥珀酸脱氢酶抑制剂（SDHI）类杀菌剂，因其高效和作用机制新颖被广泛用于土壤线虫的防治。本文以杀菌、杀线虫剂氟吡菌酰胺为分子骨架，通过引入硫醚和砜亚结构，设计合成了两个系列的结构新颖的目标化合物，并经核磁共振氢谱（1H NMR）、核磁共振碳谱（13C NMR）和高分辨质谱（HRMS）表征新结构。经生物活性测试发现，与对照药氟吡菌酰胺相比，大多数目标化合物在200 μg·mL−1浓度下显示出优异的杀线虫活性，而当浓度降低为100 μg·mL−1时，线虫死亡率大大降低，其中，化合物I-11、II-6除外。在杀菌活性方面，化合物I-9具有优异的抑菌率，其分子对接结果将为高活性杀菌先导化合物的设计和探索提供重要的理论指导。

关键词： 合成     杀线虫活性     杀菌活性     分子对接    

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标题 作者 时间 类型 操作

Hydrophilic modification of poly(aryl sulfone) membrane materials toward highly-efficient environmental

期刊论文

Effect of electrokinetic property of charged polyether sulfone membrane on bovine serum albumin fouling

Xiaorong Meng, Shanshan Huo, Lei Wang, Xudong Wang, Yongtao Lv, Weiting Tang, Rui Miao, Danxi Huang

期刊论文

Synthesis, molecular docking and antibacterial evaluation of 2-(4-(4-aminophenylsulfonyl)phenylamino)-3-(thiophen-2-ylthio)naphthalene-1,4-dione derivatives

Palanisamy RAVICHANDIRAN, Dhanaraj PREMNATH, Samuel VASANTHKUMAR

期刊论文

含硫醚和砜亚结构的新型芳香酰胺类衍生物的设计、合成及生物活性

华学文, 刘南南, 周沙, 张蕾蕾, 殷昊, 王桂清, 范志金, 马翼

期刊论文