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Frontiers of Medicine >> 2023, Volume 17, Issue 6 doi: 10.1007/s11684-023-1043-5

Pathogen evolution, prevention/control strategy and clinical features of COVID-19: experiences from China

Received: 2023-06-13 Accepted: 2023-12-27 Available online: 2023-12-27

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Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was reported at the end of 2019 as a worldwide health concern causing a pandemic of unusual viral pneumonia and many other organ damages, which was defined by the World Health Organization as coronavirus disease 2019 (COVID-19). The pandemic is considered a significant threat to global public health till now. In this review, we have summarized the lessons learnt during the emergence and spread of SARS-CoV-2, including its prototype and variants. The overall clinical features of variants of concern (VOC), heterogeneity in the clinical manifestations, radiology and pathology of COVID-19 patients are also discussed, along with advances in therapeutic agents.

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