LDL adsorbent with dendrimer PAMAM as spacer

2008, Volume 2, Issue 4

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Frontiers of Chemical Science and Engineering >> 2008, Volume 2, Issue 4 doi: 10.1007/s11705-008-0084-2

LDL adsorbent with dendrimer PAMAM as spacer

1.Department of Biochemical Engineering, School of Chemical Engineering and Technology, Tianjin University; 2.The Key Laboratory of Bioactive Materials, Ministry of Education, Nankai University;

Available online: 2008-12-05

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Abstract

Dendritic polymers are three-dimensional, highly ordered compounds formed by reiterative reaction sequences, and via discrete stages referred to as generations. To study the spacer effect of low density lipoprotein (LDL) adsorbent, we linked dendrimer polyamidoamine (PAMAM) generation 1 (G1), generation 3 (G3) and generation 5 (G5) to cellulose beads, respectively, and then determined the adsorption proportion of the adsorbents with PAMAM decorated with taurine. The result shows that the spacer with activated multi-points could efficiently improve the adsorption capacity of the adsorbent.

Keywords

adsorption proportion ; adsorbent ; dendrimer polyamidoamine ; reiterative ; generation

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