我国海洋温差能资源量巨大，主要分布在广东省和南海海域，是区域能源结构优化以实现碳达峰、碳中和的有效支撑，也是未来我国南海、21世纪海上丝绸之路沿线诸多岛屿能源补给保障的重要途径；目前海洋温差能发电（ OTEC）技术和装备尚处于实验阶段，兆瓦级试验电站建设成本巨大，整体技术成熟度不及商业级利用规模，亟待发展突破。本文总结了国内外OTEC及综合利用的发展模式、技术装备所面临的挑战，针对南海温差能资源开发困境、广东省液化天然气（ LNG）冷能资源浪费等情况，提出了以LNG气化的低温海水替代深层海水进行温差能发电的新途径。建议以珠海LNG气化站为例，探索LNG冷能回收–温差能发电、低温冷海水综合利用示范基地的发展模式；通过初步概算示范基地的投资与收益，完成了相应模式的经济与技术可行性论证。相关发展模式建议、应用案例论证过程，可为我国温差能与低温海水资源综合利用提供技术借鉴和应用参考。

China has a huge amount of ocean temperature difference energy resources that are primarily distributed in Guangdong Province and the South China Sea. These resources are crucial for optimizing the energy structure of Guangdong Province and for ensuring the energy supply of islands in the South China Sea and along the 21st Century Maritime Silk Road. Currently, the ocean thermal energy conversion (OTEC) technology and equipment are still in the experimental stage worldwide. The construction cost of megawatt-level experimental power stations is huge, and its overall technologies are not mature enough for commercial utilization; therefore, breakthroughs in related technologies and equipment are urgently needed. In this article, we summarize the development mode of OTEC and the challenges faced by related technologies and equipment in China and abroad. We propose a new approach of using low-temperature seawater—produced during the gasification of liquefied natural gas (LNG)—instead of deep seawater to generate electricity; this can help overcome the difficulties regarding the temperature difference energy development in the South China Sea and address the waste of LNG cold energy resources in Guangdong Province. Specifically, we use the Zhuhai LNG gasification station as an example to explore a development model of integrating LNG cold energy recovery with OTEC and the establishment of a low-temperature seawater comprehensive utilization demonstration base. Moreover, we demonstrate the economic and technical feasibility of the model through a preliminary estimate of the investment and revenue of the demonstration base. This case is expected to provide necessary technical references and application demonstrations for the comprehensive utilization of temperature difference energy and low-temperature seawater resources in China.