生命科学及医学新型研发机构是新一轮科技革命和产业变革的产物；在新的历史条件下，加速相关成果转化，对于培育生物医药领域国家战略科技力量、壮大我国生物医药产业、实现生物医药科技自立自强具有重大战略意义。本文立足生命科学及医学新型研发机构成果转化呈现的新态势，通过文献调研、实地调研考察，深入分析了国内外相关研发机构成果转化的经验，总结得出了4 种生命科学及医学新型研发机构运行转化模式；聚焦生命科学及医学新型研发机构成果转化“核心 ‒催化”系统，研究符合创新规律和市场规律的成果转化机制体系，构建了生命科学及医学新型研发机构成果转化机制“微生态”模型，包括技术研发、技术实施、投资系统3 个核心系统以及政府宏观支撑催化系统。研究建议，聚焦顶层设计、营造创新生态、激活转化动力和强化制度支撑，以期为我国生命科学及医学新型研发机构加速推进成果转化提供理论与实践参考。

Novel research and development (R&D) institutions in life sciences and medicine are the products of the latest round of technological revolution and industrial transformation. Under these new historical circumstances, accelerating the transformation of achievements from these novel R&D institutions is of strategic significance for cultivating national technological strength in the field of biomedicine, strengthening China’s biopharmaceutical industry, and achieving self-reliance in biomedical science and technology.This study presents the new dynamic of achievement transformation in novel R&D institutions in life sciences and medicine, conducts an in-depth analysis of related experience from both China and abroad through a literature review and field investigation, and summarizes four operational transformation modes of these institutions. Focusing on the “core-catalyst” system of achievement transformation in these novel R&D institutions, we research the achievement transformation mechanism system that adheres to the principles of innovation and market rules, and propose a micro-ecological model for achievement transformation mechanisms in these novel R&D institutions, including three core systems (i.e., technology R&D, technology implementation, and investment systems) and a government macro-support catalytic system. Policy recommendations are offered with an emphasis on top-level design, creating an innovative ecosystem, activating transformation dynamics, and strengthening system support, to provide theoretical and practical references for accelerating the transformation of achievements from Chinese novel R&D institutions in life sciences and medicine.