采用五因素五水平二次通用旋转组合设计方案（1/2实施），在盆栽条件下，不同水分状况氮素对冬小麦产量的影响。通过建立回归模型及对其进行解析和寻优分析，得出如下结论：各试验因素对冬小麦籽粒产量影响的大小顺序为土壤含水量＞越冬期施氮＞拔节期施氮＞灌浆期施氮＞苗期施氮。施氮关键时期为越冬期、拔节期；苗期施氮和土壤含水量及越冬期施氮和土壤含水量交互效应显著，其中越冬期施氮和土壤含水量比苗期施氮和土壤含水量交互作用更为显著。

By using the quadratic general spinning design, pot experiments were conducted to study the comprehensive effect of the stage and rate of N fertilizer application under different status of soil moisture on winter wheat yield systematically. The results showed that the mathematical model established based on the result of experiments is significant. By analysing the mathematical model, the soil moisture, tillering and jointing stage were thought to be the remarkable factors, while the influencing sequence from large to small is： soil moisture ＞ tillering stage ＞ jointing stage ＞ milking stage ＞ seedling stage; The interaction effects exist between different factors.