尿激酶型纤溶酶原激活系统是纤溶系统的重要组成部分，它通过水解细胞外间质，参与组织改造和细胞迁移，在肿瘤细胞的侵袭和转移中发挥作用；讨论了uPA系统的结构、作用机理及与子宫内膜癌的关系，旨在为子宫内膜癌的诊断和治疗提供新方法。

Urokinase-type plasminogen actor (uPA)system is a essential member of plasmin system. uPA system participates in the reconstruction of tissues and immigration of tumor cells by the degradation of the extracellular matrix, and then takes a important role in the invasion and metastasis of malignant tumors. This article is about the relationship beween uPA system and carcinoma of endometrium, in order to provide some new ideas for the diagnosis and theraphy of carcinoma of endometrium.