模拟生物免疫机理实现计算网格的性能抗衰是一个崭新的研究方向。分析和比较了免疫和抗衰之间的异同，构建了基于免疫Agent的系统抗衰逻辑模型，模拟生物免疫机理对计算网格的资源和性能进行监控和诊断，建立性能衰退的数学模型，并给出了抗衰策略决策方法。以一个分布式的音像资源事务处理系统为背景进行应用研究，给出了一个两阶段超指数分布的数学模型来评估性能，结果表明该方法是有效的。

Simulating biological immune mechanism to implement performance rejuvenation is a new research approach for computing grid.  This paper analyzes and compares the immune process's characteristics and computing system's rejuvenation,  sets up the logical model of system rejuvenation based on immune agent above simulates the biological immune mechanisms to monitor resource usage and diagnose performance degradation, constructs the mathematics model,  then puts forward a method to make decision for rejuvenation policy.  On the basis of above an application regarding audio-video resource transaction process system as background is studied,  a two-stage hyper-exponential model is proposed to evaluate system performance.  The results of case study indicate that this method is effective and feasible.