中国航天工程质量管理以钱学森系统工程理论为指导，以“坚持、完善、发展”为原则，以完成重大工程任务为牵引，不断进行理论和管理创新。“十一五”以来，航天科技集团实施了航天型号精细化质量管理，保证了载人航天、嫦娥工程等一系列重大航天任务的圆满成功。精细化质量管理强调持续提升总体设计、整体优化、有效地识别与控制技术风险及快速聚焦、放大和量化控制关键细节的能力，强调单位质量管理体系和项目产品保证体系的有机结合和有效运行，强调实用的管理工具的开发和应用，强调技术、产品、队伍和管理成熟度的同步提升。笔者简要回顾了航天质量管理的发展历程，提出了航天工程精细化质量管理的概念和内涵，论述了精细化质量管理的理论、方法和体系及管理实践的主要做法。

China's aerospace project quality management is guided by Dr. Qian Xuesen’s system engineering theory. Based on the principle of “adherence, perfect and development”, driven by the major engineering projects, the theory and management innovation of aerospace project quality management has been continuously developed. Since the “11th Five-Year Plan”, CASC has been implemented aerospace project meticulous quality management to ensure the success of a series of major aerospace projects, such as China’s manned aerospace project , Chang’e project, etc. The meticulous quality management puts the emphasis on improving the capabilities of overall design improvement, system optimization, effectively identification and control of the technical risk, fast focusing, and amplifying and quantizing control capability of key details; highlights the effective integration and operation of organizational quality management system and project product assurance system; focuses on the development and application of the practical management tools and the synchronous improvement of technology, product, team and management maturity. This paper briefly reviewed the history of the development of quality management in aerospace industry, and proposed the concept and content meticulous quality management, and discusses the meticulous quality management theoretical basis, methods, work systems and the main approaches.