采用酶联免疫吸附试验(ELISA) 对2013 年1 月—2013 年12 月进行孕前筛查和孕早期普查的2 046 例妇女进行TORCH 特异性IgM 和IgG 抗体检测，主要检测RV-IgG、TOXO-IgG、TOXO-IgM、CMVIgG、CMV-IgM 五项。在调查的2 046 例妇女中，TORCH-IgM 总阳性率为0. 88 %，其中以巨细胞病毒(CMV)感染率居高，为0.68%，弓形虫（TOXO）为0. 20%。TORCH－IgG 阳性率以CMV最高，达97.65 %，其次为RV-IgG、TOXO-IgG，分别为85.58 %和4.89 %。广州市孕前和孕早期妇女TORCH感染率较高，应该积极进行监测和宣传，早发现，早干预，提高出生人口素质，减少出生缺陷与残疾发生。

To investigate the infective rates of toxoplasma，Rubella virus，cytomegalovirus，herpes simplex virus (TORCH ) in unborn child and pregnant women in Guangzhou City and offer the reference for maternity and child care．We detected the TORCH IgM and IgG from Jan 2013 to December 2013，serum samples from 2 046 women before pregnancy and in the early period of pregnancy in our research institute were tested by ELISA. In the survey of 2 046 women，the total positive rate of TORCH-IgM was 0.88 %，with the higher positive Rates of CMV (0.68 %) and TOX(0.20 %). In the positive Rates of TORCH-IgG，CMV was the highest，up to 97.65 %，followed by RV (85.58 %) and TOXO (4.89 %)．The infective rate of TORCH is pretty high in women before pregnancy and in the early period of pregnancy in Guangzhou，monitor actively and strengthen publicity of TORCH，early detection and early intervention，improving the quality of premarital births and reducing the occurrence of birth defects and disabilities．