This article comprehensively summarize the optimization of process innovation of the new generation of high-speed electric multiple unit（EMU）， minutely analysize its innovative design on aerodynamic optimization， air tightness， modal matching， reduction vibration and noise， lightweight and other aspects. The simulation and experiment result shows that the new generation of high-speed EMU is with enough strength， stiffness， structure stability， excellent features of vibration and fatigue，great performance aerodynamics and noise.