Ultra low permeability formations in outer area of Daqing western is characterized by deeply buried, thin, and sand scattered. Note that first waterflood in such formation where water contained capability is poor and it's difficult to recovery oil efficiently, this paper describes pilot studies of pressurized water injection on single well to ensure effective waterflood drive and achieve goal of “sufficient water injected and implementation well” on the basis of thorough theoretical study and many demonstration. After injection completion, effective waterflood drive and significant production improvement was achieved.Use of passive seismic monitoring and isotope logging has increased water contained capabilities, eased the complexity contradiction between layers, and improved reservoir effectiveness. Water injection front drive and spread area increases or decreases, following changes of pressure of water injection. Pressurized water injection can increase coefficient of water injection front drive and enhance oil recovery, improve development efficiency of ultra low permeability reservoir,it provides a reference for development of ultra low permeability oilfield.