Based on the concept of full-scale mining,that is,the concept of research on the mining and utilizing of mineral resources of multi-deposits in a mine area by systematic and dynamic considering of mine full-life process, a synthetic optimizing model of artificial neutral network (ANN) export system is set up.By using the model ,a synthetic optimization for the mining and utilization deposits at Gushan mine area is carried out, and the suggested ore production scale for the Gushan mine area is 5.4～6.8 million t/a. The optimized results are helpful to the strengthening construction, the improvement of economical and social benefit and the sustainable development of Gushan mine area.