Karst disaster is badly endangering the safety of tunnel construction and impedes the construction schedule seriously. In present, it is an important and difficult problem in tunnel construction all over the world. The feature of karst water burst in Maluqing Tunnel is analyzed first, and then advanced geological forecasting technology, hydrological observation, reverse slope drainage technology and water release technology in the treatment for the +978 Karst cave are introduced separately; what is more, disclosure progress and the status after disclosing of the +978 Karst cave are depicted detailedly. Finally, curtain grouting technology for stratum consolidation and pile-cap technology for spanning karst cave after the +978 Karst Cave disclosed are introduced too. Successful experience for the karst treatment in Maluqing Tunnel will provide a reference to the treatment for karst cave with large quantity water during the similar tunnel construction in the future.