Design structure matrix is applied to the collaborative design process for complex products. The recognition problem of coupling activities in DSM can be solved by graph theory knowledge. And a method for reconfiguration of DSM blocking is presented according to the principles. Then, reengineering for a design process is proposed by decomposing and tearing the blocked activities to shorten the cycle of design and reduce the cost of development. Finally, a case, the aircraft design process reconfiguration with DSM, is presented.