The research on the earthquakes and the landslides in the Three Gorges east segment (Wuxia Gorge—Xilingxia Gorge) of the Yangtze River shows that there is a close relation among the active fault zones, the seismic spread bands and the landslide mobile belts, which is embodied in the overlap of spatial distribution, the tally of temporal period as well as the consistency of active intensity. They stand for some major features of the regional crust movement. It must be stressed that there are two pleistoseismic occurring zones through the Three Gorges Reservoir region, known as “ Qianjiang - Enshi - Badong” and “Xiannushan — xiangxi — Xingshan”. Before the engineering treatments of geological hazards, therefore, the trigger action of the potential seismic motion to landslide and hazardous rock body must be fully taken into account.