A concept of two different reaction zones was proposed based on the FCC reaction mechanism. The concept was used to design a novel reactor with corresponding engineering measures. Experiments were conducted on the newly developed reaction system. The test run results of the 1.4 Mt/a MIP commercial unit showed that mass yield of dry gas was reduced by 0.41 % and mass yield of slurry was reduced by 0.99% , while mass yield of light ends was increased by 1.17%. The volume fraction of olefin in the cracked naphtha dropped by 14.1% while the volume fraction of isoparaffin increased by 12.9% and the mass fraction of sulfur was reduced by 26.5% with maintaining the octane rating index unchanged and a significant extension of the induction period compared with the conventional FCC process.