China is a country with high seismicity. It is very important for industry and structure to fortify against earthquake. In the paper the outline of seismicity in China, the criteria for fortification against earthquake and contents of seismic zonation map of China are described. The contents of seismic safety evaluation for major construction project, such as large dams, large bridges, long distance pipe lines for transporting oil and natural gas, nuclear plants, petrochemical enterprises and so on, are presented. Some geological disasters caused by destructive earthquake, such as earthquake-caused collapse and landslide, liquefaction of saturated soil and earthquake fault and so on, are also presented. Preventive countermeasure for these disasters is discussed.