Golmud City, located in the western part of Qinghai Province, is known as one of the boomtown in the arid northwestern China, so the problems of water utilization are major factors dominating its future. Suggestions on achieving balance between water supply and demand, harmony between mankind and flood in flood control and disaster mitigation are proposed in the paper. According to the development of modern city in the request of the 21st century, it ought to change the present situation of water use for agriculture and industry as well as treatment for water pollution of Golmud City.