In his career path from a scientist to a thinker, Prof. Qian Xuesen has persistently emphasized the important role of organization and management. This paper discussed his advisory contributions to the development of management science of China, including pointing out that raising ideological cognition is the priority for developing management science, emphasizing the role of system engineering in organization and management, advocating considering and solving problem from a holistic point of view, promoting the integration of natural science with social science, insisting on developing management science according to Chinese characteristics.