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公共场所人群聚集社会风险的研究

李剑峰,刘茂,隋晓琳

《中国工程科学》 2007年 第9卷 第6期   页码 88-93

摘要: 进而推导出事故灾害频率的定量模型;同时通过统计不同严重程度(死亡人数)事故 的发生次数,用其发生频率表征其发生的条件概率,根据计算得到的死亡事故发生概率,即可得到不同死亡人 数事故的发生概率,最终得到F-N。运用F-N就可以分析公共场所人群聚集的社会风险。以公共场所 部分事故统计为参考数据,描述使用该模型的步骤,结果表明该模型具有一定的合理性和准确性。

关键词: 人群聚集风险     社会风险     F-N     定量风险分析    

Pressure drop analysis on the positive half-cell of a cerium redox flow battery using computational fluid dynamics: Mathematical and modelling aspects of porous media

Fernando F. Rivera, Berenice Miranda-Alcántara, Germán Orozco, Carlos Ponce de León, Luis F. Arenas

《化学科学与工程前沿(英文)》 2021年 第15卷 第2期   页码 399-409 doi: 10.1007/s11705-020-1934-9

摘要: Description of electrolyte fluid dynamics in the electrode compartments by mathematical models can be a powerful tool in the development of redox flow batteries (RFBs) and other electrochemical reactors. In order to determine their predictive capability, turbulent Reynolds-averaged Navier-Stokes (RANS) and free flow plus porous media (Brinkman) models were applied to compute local fluid velocities taking place in a rectangular channel electrochemical flow cell used as the positive half-cell of a cerium-based RFB for laboratory studies. Two different platinized titanium electrodes were considered, a plate plus a turbulence promoter and an expanded metal mesh. Calculated pressure drop was validated against experimental data obtained with typical cerium electrolytes. It was found that the pressure drop values were better described by the RANS approach, whereas the validity of Brinkman equations was strongly dependent on porosity and permeability values of the porous media.

关键词: CFD simulation     porous media     porous electrode     pressure drop     redox flow battery    

Synthesis and properties of water-soluble 1,9-dialkyl-substituted BF

Dan Wu, Gonzalo Durán-Sampedro, Donal F. O’Shea

《化学科学与工程前沿(英文)》 2020年 第14卷 第1期   页码 97-104 doi: 10.1007/s11705-019-1828-x

摘要: Bis-alkylsulfonic acid and polyethylene glycol (PEG)-substituted BF azadipyrromethenes have been synthesized by an adaptable and versatile route. Only four synthetic stages were required to produce the penultimate fluorophore compounds, containing either two alcohol or two terminal alkyne substituents. The final synthetic step introduced either sulfonic acid or polyethylene glycol groups to impart aqueous solubility. Sulfonic acid groups were introduced by reaction of the bis-alcohol-substituted fluorophore with sulfur trioxide, and a double Cu(I)-catalyzed cycloaddition reaction between the bis-alkyne fluorophore and methoxypolyethylene glycol azide yielded a neutral bis-pegylated derivative. Both fluorophores exhibited excellent near-infrared (NIR) photophysical properties in methanol and aqueous solutions. Live cell microscopy imaging revealed efficient uptake and intracellular labelling of cells for both fluorophores. Their simple synthesis, with potential for last-step structural modifications, makes the present NIR-active azadipyrromethene derivatives potentially useful as NIR fluorescence imaging probes for live cells.

关键词: NIR-fluorophores     live cell imaging     NIR-AZA    

Compiling of comprehensive data of human infections with novel influenza A (H7N9) virus

null

《医学前沿(英文)》 2013年 第7卷 第3期   页码 275-276 doi: 10.1007/s11684-013-0285-z

Best operating conditions to produce hydroxyapatite nanoparticles by means of a spinning disc reactor

F. D’ Intino,B. de Caprariis,M.L. Santarelli,N. Verdone,A. Chianese

《化学科学与工程前沿(英文)》 2014年 第8卷 第2期   页码 156-160 doi: 10.1007/s11705-014-1427-9

摘要: In this work, Mg doped hydroxyapatite (Mg-HAP) nanoparticles were produced by a reaction-precipitation process by using a spinning disc reactor (SDR) at high rotational speed. The production process of these nanoparticles consisted of the neutralization reaction between two aqueous solutions of calcium chloride and ammonia orthophosphate at room temperature. By operating at pH= 10, a high purity Mg-HAP nanoparticles were obtained. In particular, they were 51 nm in average size when the two reagents were fed over the disc symmetrically at 3 cm from the disc center and a rotational speed of the disc reactor equal to 1400 r/min was adopted.

关键词: hydroxyapatite     nanoparticles     spinning disc reactor    

Synthesis of a cardanol-amine derivative using an ionic liquid catalyst

E. da Silva, Roselayne F. Furtado, Zengshe Liu, H. N. Cheng

《化学科学与工程前沿(英文)》 2016年 第10卷 第3期   页码 425-431 doi: 10.1007/s11705-016-1581-3

摘要: Cardanol is a biobased raw material derived from cashew nut shell liquid. In order to extend its utility, new derivatives and additional applications are useful. In this work cardanol was first epoxidized, and a novel aniline derivative prepared from it under mild reaction conditions with the help of an ionic liquid catalyst. The reaction chemistry was studied by using nuclear magnetic resonance. The resulting aminohydrin adduct showed antioxidant property and should also be a useful synthon for further reactions. As an example, the aminohydrin was shown to undergo a condensation reaction with formaldehyde to form a prepolymer, which could be further reacted to form thermosetting resins.

关键词: cardanol     epoxidation     aminohydrin     aniline     ionic liquid     aniline-formaldehyde    

Avian influenza A: an avian influenza virus from low pathogenic to highly pathogenic

Liu, Haixia Xiao, Lianpan Dai, Di Liu, Jianjun Chen, Xiaopeng Qi, Yuhai Bi, Yi Shi, George F.

《医学前沿(英文)》 2021年 第15卷 第4期   页码 507-527 doi: 10.1007/s11684-020-0814-5

摘要: The avian influenza A (H7N9) virus is a zoonotic virus that is closely associated with live poultry markets. It has caused infections in humans in China since 2013. Five waves of the H7N9 influenza epidemic occurred in China between March 2013 and September 2017. H7N9 with low-pathogenicity dominated in the first four waves, whereas highly pathogenic H7N9 influenza emerged in poultry and spread to humans during the fifth wave, causing wide concern. Specialists and officials from China and other countries responded quickly, controlled the epidemic well thus far, and characterized the virus by using new technologies and surveillance tools that were made possible by their preparedness efforts. Here, we review the characteristics of the H7N9 viruses that were identified while controlling the spread of the disease. It was summarized and discussed from the perspectives of molecular epidemiology, clinical features, virulence and pathogenesis, receptor binding, T-cell responses, monoclonal antibody development, vaccine development, and disease burden. These data provide tools for minimizing the future threat of H7N9 and other emerging and re-emerging viruses, such as SARS-CoV-2.

关键词: H7N9     HPAIV     epidemiology     clinical features     pathogenesis     hemagglutinin     immunity     vaccine    

Antifungal and antibacterial functions of medicinal leech recombinant destabilase-lysozyme and its heated-up derivative

YUDINA, Danyang GUO, N. F. PISKUNKOVA, I. B. PAVLOVA, L. L. ZAVALOVA, I. P. BASKOVA

《化学科学与工程前沿(英文)》 2012年 第6卷 第2期   页码 203-209 doi: 10.1007/s11705-012-1277-2

摘要: Antifungal activity of recombinant medicinal leech destabilase-lysozyme (rec.Dest-Lys) was investigated by using fungi: , and , including yeasts and . Its antibacterial activity was investigated on gram-negative bacteria . These activities were assessed by radial agar diffusion assay, and scanning and transmission electron microscopy. Therefore, destabilase-lysozyme not only is endo-isopeptidase and lysozyme, but also has antifungal and antibacterial activities. Muramidase activity of rec.Dest-Lys disappeared after heat-treating at 90°C for 50 min without the loss of its antimicrobial activity. Furthermore we showed for the first time that the heated-up derivative of rec.Dest-Lys exhibited more potent activities against the above enumerated fungi and gram-negative bacteria than original protein.

关键词: recombinant destabilase-lysozyme (rec.Dest-Lys)     antimicrobial activity     antifungal activity     medicinal leech     heated-up derivative of rec.Dest-Lys (T-rec.Dest-Lys)    

基于机器学习的自动化恶意代码分类与新恶意代码检测技术 Article

Liu LIU, Bao-sheng WANG, Bo YU, Qiu-xi ZHONG

《信息与电子工程前沿(英文)》 2017年 第18卷 第9期   页码 1336-1347 doi: 10.1631/FITEE.1601325

摘要: 恶意软件的爆炸式增长对信息安全构成重大威胁。基于签名机制的传统反病毒系统无法将未知的恶意软件分类到相应的恶意家族和检测新的恶意软件。因此,我们提出一种基于机器学习的恶意软件分析系统,由数据处理系统,决策系统和新的恶意软件检测系统三个子系统组成。数据处理系统包含灰度图像的纹理特征,Opcode特征和API特征等三种特征提取方法。决策系统被用来分类恶意软件和证实可疑的恶意软件。最后,检测系统使用共享近邻聚类算法(shared nearest neighbor, SNN)来发现新的恶意软件。我们在Kingsoft,,ESET NOD32和Anubis收集的二万多恶意样本集上对所提出的方法进行了评估。结果表明,我们的系统可以有效地分类未知恶意软件,准确率可达98.9%。同时新恶意软件的成功检测率为86.7%。

关键词: 恶意代码分类;机器学习;n-gram;灰度;特征提取;恶意代码检测    

Development of soft kernel durum wheat

Craig F. MORRIS

《农业科学与工程前沿(英文)》 2019年 第6卷 第3期   页码 273-278 doi: 10.15302/J-FASE-2019259

摘要:

Kernel texture (grain hardness) is a fundamental and determining factor related to wheat ( spp.) milling, baking and flour utilization. There are three kernel texture classes in wheat: soft and hard hexaploid ( ), and very hard durum ( subsp. ). The genetic basis for these three classes lies with the Puroindoline genes. Phenotypically, the easiest means of quantifying kernel texture is with the Single Kernel Characterization System (SKCS), although other means are valid and can provide fundamental material properties. Typical SKCS values for soft wheat would be around 25 and for durum wheat≥80. Soft kernel durum wheat was created via homeologous recombination using the mutation, which facilitated the transfer of ca. 28 Mbp of 5DS that replaced ca. 21 Mbp of 5BS. The 5DS translocation contained a complete and intact locus and both puroindoline genes. Expression of the puroindoline genes in durum grain resulted in kernel texture and flour milling characteristics nearly identical to that of soft wheat, with high yields of break and straight-grade flours, which had small particle size and low starch damage. Dough water absorption was markedly reduced compared to durum flour and semolina. Dough was essentially unchanged and reflected the inherent gluten properties of the durum background. Pasta quality was essentially equal-to-or-better than pasta made from semolina. Agronomically, soft durum germplasm showed good potential with moderate grain yield and resistance to a number of fungal pathogens and insects. Future breeding efforts will no doubt further improve the quality and competitiveness of soft durum cultivars.

关键词: soft durum wheat     grain hardness     puroindolines     milling     baking     pasta     noodles    

组织工程模板中的生物相容性途径 Perspective

David F. Williams

《工程(英文)》 2018年 第4卷 第2期   页码 286-290 doi: 10.1016/j.eng.2018.03.007

摘要:

组织工程通过系统结合分子信号和力学信号对特定靶细胞进行有意可控刺激以组建新的组织,通常需要借助由生物材料构建的结构传递这些信号,并对生成的组织块塑形。这些结构之前被称为支架,如今被更准确地命名为模板,其规范却难以定义,主要因为该规范必须涉及为细胞组建新组织提供适宜的微环境,以及细胞与模板材料的相互作用符合构建新型可存活组织的需求。这些特点统称为生物相容性。然而,传统生物相容性的理论和公认机制(大多通过可移植的医学装置进行实验得出)不足以解释在组织工程过程中的现象。本文作者近期在特定的基于材料、生物学的途径方面重新定义了生物相容性。本文以上述途径为前提讨论了组织工程生物相容性的机制。

关键词: 生物材料     支架     机械力转导     炎症     拓扑    

Resistance of large deformation of the Wushaoling Tunnel F7 soft fault

ZHAO Xufeng, CHEN Haiming, WANG Chunmiao

《结构与土木工程前沿(英文)》 2007年 第1卷 第1期   页码 123-127 doi: 10.1007/s11709-007-0013-3

摘要: In this article, the mechanical characteristics of the squeeze of the F7 fault of the Wushaoling Tunnel are analyzed. The measurements and techniques are proposed to resist the deformation. The result indicates that the method of construction to control the further squeeze deflection is appropriate.

关键词: F7     deformation     appropriate     construction     mechanical    

大规模计算系统综述 Review

Ning LIU, Dong-sheng LI, Yi-ming ZHANG, Xiong-lve LI

《信息与电子工程前沿(英文)》 2020年 第21卷 第3期   页码 384-404 doi: 10.1631/FITEE.1900127

摘要: 是描述实体之间关系的一种重要数据结构。现实世界中许多应用领域非常依赖数据。然而,由于计算应用与传统应用的显著差异,利用通用平台处理计算应用是低效的,这极大推动了专用计算系统的研究。本综述系统地对算法和计算应用进行分类,将现有计算系统划分为通用和专用系统,并详细总结。深入分析计算系统的实现技术,包括编程模型、分区策略、通信模型、执行模型和容错机制。最后,分析计算领域最新进展,并提出有待进一步研究的4个问题。

关键词: 算法;计算应用;计算系统    

论文演化:学术文献多视角结构化检索 None

Dan-ping LIAO, Yun-tao QIAN

《信息与电子工程前沿(英文)》 2019年 第20卷 第2期   页码 187-205 doi: 10.1631/FITEE.1700105

摘要: 提出一种为学术文献建立结构化检索结果的方法,称为论文演化(PEG)。PEG采用多个演化链描述查询输入信息在不同主题方向的演化情况。PEG构造主要有3个步骤:首先,采用元分解法把文献软聚合为多个群落,获取每篇论文的主题分布;其次,从与查询相关的文献群落中提取主题连贯性演化链。每条演化链反映查询信息的某一视角;最后,提取的演化链组合形成论文演化,可以覆盖查询涉及的所有主题。基于真实文献数据库的实验结果表明,该方法能够建立对用户有意义的论文演化

关键词: 论文演化;学术文献检索;元分解;主题连贯性    

未来网络专辑:软件定义网络 Editorial

Tao HUANG,F. Richard YU,Yun-jie LIU

《信息与电子工程前沿(英文)》 2016年 第17卷 第7期   页码 603-605 doi: 10.1631/FITEE.SDN2016

摘要:

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标题 作者 时间 类型 操作

公共场所人群聚集社会风险的研究

李剑峰,刘茂,隋晓琳

期刊论文

Pressure drop analysis on the positive half-cell of a cerium redox flow battery using computational fluid dynamics: Mathematical and modelling aspects of porous media

Fernando F. Rivera, Berenice Miranda-Alcántara, Germán Orozco, Carlos Ponce de León, Luis F. Arenas

期刊论文

Synthesis and properties of water-soluble 1,9-dialkyl-substituted BF

Dan Wu, Gonzalo Durán-Sampedro, Donal F. O’Shea

期刊论文

Compiling of comprehensive data of human infections with novel influenza A (H7N9) virus

null

期刊论文

Best operating conditions to produce hydroxyapatite nanoparticles by means of a spinning disc reactor

F. D’ Intino,B. de Caprariis,M.L. Santarelli,N. Verdone,A. Chianese

期刊论文

Synthesis of a cardanol-amine derivative using an ionic liquid catalyst

E. da Silva, Roselayne F. Furtado, Zengshe Liu, H. N. Cheng

期刊论文

Avian influenza A: an avian influenza virus from low pathogenic to highly pathogenic

Liu, Haixia Xiao, Lianpan Dai, Di Liu, Jianjun Chen, Xiaopeng Qi, Yuhai Bi, Yi Shi, George F.

期刊论文

Antifungal and antibacterial functions of medicinal leech recombinant destabilase-lysozyme and its heated-up derivative

YUDINA, Danyang GUO, N. F. PISKUNKOVA, I. B. PAVLOVA, L. L. ZAVALOVA, I. P. BASKOVA

期刊论文

基于机器学习的自动化恶意代码分类与新恶意代码检测技术

Liu LIU, Bao-sheng WANG, Bo YU, Qiu-xi ZHONG

期刊论文

Development of soft kernel durum wheat

Craig F. MORRIS

期刊论文

组织工程模板中的生物相容性途径

David F. Williams

期刊论文

Resistance of large deformation of the Wushaoling Tunnel F7 soft fault

ZHAO Xufeng, CHEN Haiming, WANG Chunmiao

期刊论文

大规模计算系统综述

Ning LIU, Dong-sheng LI, Yi-ming ZHANG, Xiong-lve LI

期刊论文

论文演化:学术文献多视角结构化检索

Dan-ping LIAO, Yun-tao QIAN

期刊论文

未来网络专辑:软件定义网络

Tao HUANG,F. Richard YU,Yun-jie LIU

期刊论文