Search scope:
排序: Display mode:
Molecular engineering of dendrimer nanovectors for siRNA delivery and gene silencing
Yu Cao, Xiaoxuan Liu, Ling Peng
Frontiers of Chemical Science and Engineering 2017, Volume 11, Issue 4, Pages 663-675 doi: 10.1007/s11705-017-1623-5
Keywords: gene therapy RNAi therapeutics dendrimer nanovectors gene silencing
Profiling influences of gene overexpression on heterologous resveratrol production in
Duo Liu,Bingzhi Li,Hong Liu,Xuejiao Guo,Yingjin Yuan
Frontiers of Chemical Science and Engineering 2017, Volume 11, Issue 1, Pages 117-125 doi: 10.1007/s11705-016-1601-3
Keywords: resveratrol aromatic amino acid DNA assembly metabolic engineering gene overexpression
Wang Ruiku
Strategic Study of CAE 2006, Volume 8, Issue 5, Pages 25-28
Keywords: ECIWO gene engineering solution acquiring polygene intensifying anticipant characters
Advances in genetic engineering of domestic animals
Shaohua WANG,Kun ZHANG,Yunping DAI
Frontiers of Agricultural Science and Engineering 2016, Volume 3, Issue 1, Pages 1-10 doi: 10.15302/J-FASE-2016085
Keywords: CRISPR TALEN ZFN gene editing livestock pig cattle
The Industry of Genetic Engineering
Shi Yuanchun
Strategic Study of CAE 2000, Volume 2, Issue 7, Pages 34-38
This article explains that modern biotechnology not only has a powerful spreading, driving force and economic value, but it also reserves a great potential to relax the global pressures from population, food, natural resources and environment. None of ohter technologies have such a power, or can replace biotechnology. The article also discusses the main contents of biotechnology and its new trends of industrialization. The author holds GMO food must be put in order by both science and relevant regulations, after reviewed the background and new trends of present GMO debate. The current debate has focused on the public acceptability, trade benefit and relevant policy on GMO food. GMO food will only be interrupted for the time being, and will have another development tide under the supervision of relevant laws and regulation. Finally, the paper proposes suggestions for the countermeasure and attitude that China should hold during the development and industrialization of modern biotechnology.
Keywords: genetic engineering industry gene modified organisms (GMO) countermeasure
Pingping Liu,Jia Lv,Cen Ma,Tianqi Zhang,Xiaowen Huang,Zhihui Yang,Lingling Zhang,Jingjie Hu,Shi Wang,Zhenmin Bao,
Engineering 2022, Volume 18, Issue 11, Pages 259-259 doi: 10.1016/j.eng.2022.09.002
Keywords: online THE AUTHORS.Published repertoire behalf Engineering September genotyping Academy HD-marker approach
Xia Jiahui
Strategic Study of CAE 2000, Volume 2, Issue 11, Pages 1-11
In this paper, the study on family collection, gene mapping, gene identification and gene functiont (1; 3) (q44; p11) associated with nasopharyngeal cancer was found in 1975 at first, and human TDF geneIn 1998, GJB3, a human genetic neurological deafness gene, was identified using a novel strategy of “Gene Family-Candidate Disease Gene Cloning”,and the paper was published in Nature Geneticswas also cloned from gene function study.
Keywords: genetic disease gene mapping and cloning gene familiy-candidate disease gene cloning genome wide scan gene function study
The antibiotic resistome: gene flow in environments, animals and human beings
Yongfei Hu, George F. Gao, Baoli Zhu
Frontiers of Medicine 2017, Volume 11, Issue 2, Pages 161-168 doi: 10.1007/s11684-017-0531-x
Keywords: antibiotic resistance resistome microbiome gene flow
Reflections on the system of evaluation of gene-edited livestock
Ziyao FAN, Tianwen WU, Kui WU, Yulian MU, Kui LI
Frontiers of Agricultural Science and Engineering 2020, Volume 7, Issue 2, Pages 211-217 doi: 10.15302/J-FASE-2019303
Keywords: evaluation gene editing livestock performance safety
Frontiers of Medicine 2022, Volume 16, Issue 4, Pages 627-636 doi: 10.1007/s11684-020-0815-4
Keywords: RUNX1 gene mutation acute myeloid leukemia transcriptional repression DNA methylation
Construction of lentiviral vector carrying Rab9 gene and its expression in mouse brain
Youguo HAO, Min ZHANG, Jinzhi XU, Bitao BU, Jiajun WEI
Frontiers of Medicine 2009, Volume 3, Issue 2, Pages 141-147 doi: 10.1007/s11684-009-0041-6
Keywords: Rab9 lentivirus gene therapy gene transfer
Nan Zheng, Ziyuan Song, Yang Liu, Lichen Yin, Jianjun Cheng
Frontiers of Chemical Science and Engineering 2017, Volume 11, Issue 4, Pages 521-528 doi: 10.1007/s11705-017-1612-8
Keywords: α-helical polypeptide plant gene delivery protoplast intact leaves transfection
Stem cell gene therapy: the risks of insertional mutagenesis and approaches to minimize genotoxicity
Chuanfeng Wu, Cynthia E. Dunbar
Frontiers of Medicine 2011, Volume 5, Issue 4, Pages 356-371 doi: 10.1007/s11684-011-0159-1
Keywords: gene therapy hematopoietic stem cells insertional mutagenesis genotoxicity induced pluripotent stem cell
Optimized human factor IX expression cassettes for hepatic-directed gene therapy of hemophilia B
Ru Zhang,Qiang Wang,Lin Zhang,Saijuan Chen
Frontiers of Medicine 2015, Volume 9, Issue 1, Pages 90-99 doi: 10.1007/s11684-015-0390-2
Gene therapy provides a potential cure for hemophilia B, and significant progress has been achievedin liver-directed gene transfer mediated by adeno-associated viral vectors.vectors and hFIX expression cassette may positively contribute to the ultimate success of hemophilia B geneIn addition, the regulatory elements that control the FIX gene expression in these cassettesreconstructs of hFIX with AAV vector may potentially contribute to the creation of an efficacious gene
Keywords: factor IX hemophilia B liver-specific regulatory elements hydrodynamic gene transfer
Lu Wang
Frontiers of Medicine 2013, Volume 7, Issue 3, Pages 280-289 doi: 10.1007/s11684-013-0265-3
Many gene fusions have been recognized as important diagnostic and/or prognostic markers in humanIn recent years, novel gene fusions have been identified in cases without prior knowledge of the geneticThis review focused on advanced genome-wide screening approaches in fusion gene identification, suchas microarray-based approaches, next-generation sequencing, and NanoString nCounter gene expression systemThe fundamental rationale and strategy for fusion gene identification using each biotech platform are
Keywords: gene fusion cancer microarray next-generation sequencing NanoString nCounter system
Title Author Date Type Operation
Molecular engineering of dendrimer nanovectors for siRNA delivery and gene silencing
Yu Cao, Xiaoxuan Liu, Ling Peng
Journal Article
Profiling influences of gene overexpression on heterologous resveratrol production in
Duo Liu,Bingzhi Li,Hong Liu,Xuejiao Guo,Yingjin Yuan
Journal Article
Solution to Present Gene Engineering with ECIWO Theory——Techniques of Acquiring Polygene and Intensifying
Wang Ruiku
Journal Article
Advances in genetic engineering of domestic animals
Shaohua WANG,Kun ZHANG,Yunping DAI
Journal Article
Erratum to “Targeted Genotyping of a Whole-Gene Repertoire by an Ultrahigh-Multiplex and Flexible HD-MarkerApproach” [Engineering 13 (2022) 186–196]
Pingping Liu,Jia Lv,Cen Ma,Tianqi Zhang,Xiaowen Huang,Zhihui Yang,Lingling Zhang,Jingjie Hu,Shi Wang,Zhenmin Bao,
Journal Article
Study on Family Collection, Gene Mapping, Gene Identification and Gene Function of Human Genetic Diseases
Xia Jiahui
Journal Article
The antibiotic resistome: gene flow in environments, animals and human beings
Yongfei Hu, George F. Gao, Baoli Zhu
Journal Article
Reflections on the system of evaluation of gene-edited livestock
Ziyao FAN, Tianwen WU, Kui WU, Yulian MU, Kui LI
Journal Article
Distinct gene expression pattern of mutations coordinated by target repression and promoter hypermethylation
Journal Article
Construction of lentiviral vector carrying Rab9 gene and its expression in mouse brain
Youguo HAO, Min ZHANG, Jinzhi XU, Bitao BU, Jiajun WEI
Journal Article
Gene delivery into isolated
Nan Zheng, Ziyuan Song, Yang Liu, Lichen Yin, Jianjun Cheng
Journal Article
Stem cell gene therapy: the risks of insertional mutagenesis and approaches to minimize genotoxicity
Chuanfeng Wu, Cynthia E. Dunbar
Journal Article
Optimized human factor IX expression cassettes for hepatic-directed gene therapy of hemophilia B
Ru Zhang,Qiang Wang,Lin Zhang,Saijuan Chen
Journal Article