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Mitogen-activated protein kinase pathway inhibitors: inhibitors for diseases?
Xu WANG MS, Xiao-Wei GONG MD, PhD, Yong JIANG MD, PhD, Yu-Hua LI PhD,
Frontiers of Medicine 2010, Volume 4, Issue 1, Pages 46-53 doi: 10.1007/s11684-010-0010-0
Keywords: mitogen-activated protein kinase drug target inhibitor signal transduction disease
GONG Xiaowei, WEI Jie, LI Yusheng, CHENG Weiwei, DENG Peng, JIANG Yong
Frontiers of Medicine 2007, Volume 1, Issue 3, Pages 248-252 doi: 10.1007/s11684-007-0047-x
Keywords: control stimulation mitogen-activated growth factor process
Frontiers of Medicine 2023, Volume 17, Issue 3, Pages 534-548 doi: 10.1007/s11684-022-0953-y
Keywords: hepatitis (AIH) concanavalin A (Con A) human menstrual blood-derived stem cells (MenSCs) apoptosis mitogen-activatedprotein kinase (MAPK)
Mechanisms of connective tissue formation and blocks of mitogen activated protein kinase
Irina A SHURYGINA, Michael G SHURYGIN, Nataliya I AYUSHINOVA, Galina B GRANINA, Nikolay V ZELENIN
Frontiers of Chemical Science and Engineering 2012, Volume 6, Issue 2, Pages 232-237 doi: 10.1007/s11705-012-1286-1
Keywords: connective tissue mitogen activated protein kinase (MAPK) p38 JNK
Mechanisms of insulin resistance in obesity
Jianping Ye
Frontiers of Medicine 2013, Volume 7, Issue 1, Pages 14-24 doi: 10.1007/s11684-013-0262-6
Keywords: energy expenditure inflammation lipotoxicity mitochondria hyperinsulinemia adenosine monophosphate-activatedprotein kinase (AMPK)
The role of protein kinase C epsilon in neural signal transduction and neurogenic diseases
Yuan CHEN, Qi TIAN
Frontiers of Medicine 2011, Volume 5, Issue 1, Pages 70-76 doi: 10.1007/s11684-011-0119-9
Protein kinase C epsilon (PKC ?) is one of major isoforms in novel PKC family.
Keywords: protein kinase C ? signal transduction neurogenic disease
LIU Rong, ZENG Ji, ZHOU Xinwen, WANG Jianzhi, PEI Jinjing
Frontiers of Medicine 2008, Volume 2, Issue 3, Pages 235-238 doi: 10.1007/s11684-008-0044-8
Keywords: hyperphosphorylation PP2A activity cellular regulation siRNA siRNA transfection
Enyuan TU MD, Yongjun PAN MM, Kang ZHENG MM, Zhaohua WANG MD, Qiansheng LIANG MD, Guangtian YANG MD,
Frontiers of Medicine 2009, Volume 3, Issue 4, Pages 431-436 doi: 10.1007/s11684-009-0088-4
Keywords: tanshinone II A myocardial hypertrophy rat protein kinase B abdominal aorta coarctation
XIA Yanzhi, WAN Xuedong, DUAN Qiuhong, HE Shansu, WANG Ximing
Frontiers of Medicine 2007, Volume 1, Issue 2, Pages 200-206 doi: 10.1007/s11684-007-0038-y
Keywords: palmitate characteristic study plasma resistance
Xiaoli Song, Zhenghua Shi, Xiufen Li, Xinhua Wang, Yueping Ren
Frontiers of Environmental Science & Engineering 2019, Volume 13, Issue 2, doi: 10.1007/s11783-019-1114-7
Maillard reaction between reducing sugars and amides happened during pretreatment. Over 90 min of TAH at the optimal condition, 67.59% sludge proteins was solubilized. 15.84% soluble proteins broke down to materials with small molecular weight.
Keywords: Sludge flocs Microbial cells Hydrolysate Protein breakdown Melanoidin
Effect of PRAK gene knockout on the proliferation of mouse embryonic fibroblasts
Xiaowei GONG MD, PhD, Xiaoyan MING MD, Xu WANG MM, Daan WANG MD, Peng DENG MM, Yong JIANG MD, PhD, Aihua LIU MD, PhD,
Frontiers of Medicine 2009, Volume 3, Issue 4, Pages 379-383 doi: 10.1007/s11684-009-0073-y
Keywords: p38 regulated/activated protein kinase gene knockout cell cycle cell proliferation
Frontiers of Medicine 2022, Volume 16, Issue 3, Pages 378-388 doi: 10.1007/s11684-021-0840-y
Keywords: severe Mycoplasma pneumoniae pneumonia children proteomics Fc fragment of the IgG-binding protein mechanistic target of rapamycin kinase inhibitor
Quan LI MD , Weiming LI MD , Ping ZOU MD , Jian ZHANG BM ,
Frontiers of Medicine 2009, Volume 3, Issue 3, Pages 309-315 doi: 10.1007/s11684-009-0043-4
Keywords: graft vs host disease proteinase-activated receptor murine model hematopoietic stem cell transplantation
Effects of phosphatidylinositol 3-kinase inhibitor on human cervical carcinoma cells
Yuan ZHANG MD , Xiaoyan ZHANG MM , Yanhui LI MM , Xuan DU MM , Zehua WANG MD, PhD , Hongbo WANG MD ,
Frontiers of Medicine 2009, Volume 3, Issue 3, Pages 341-346 doi: 10.1007/s11684-009-0067-9
Keywords: human cervical cancer cells apoptosis phosphatidylinositol 3-kinase (PI3K)/Akt FLICE-like inhibitoryprotein
PAK1 is a novel cardiac protective signaling molecule
Yunbo Ke,Xin Wang,Xu Yu Jin,R. John Solaro,Ming Lei
Frontiers of Medicine 2014, Volume 8, Issue 4, Pages 399-403 doi: 10.1007/s11684-014-0380-9
We review here the novel cardiac protective effects of the multifunctional enzyme, p21-activated kinase1 (PAK1), a member of a serine/threonine protein kinase family.that provides a mechanism for specifically affecting cardiac cellular processes in which regulation of proteinphosphorylation states by protein phosphatase 2A (PP2A) predominates.
Keywords: p21-activated kinase 1 (PAK1) heart
Title Author Date Type Operation
Mitogen-activated protein kinase pathway inhibitors: inhibitors for diseases?
Xu WANG MS, Xiao-Wei GONG MD, PhD, Yong JIANG MD, PhD, Yu-Hua LI PhD,
Journal Article
Involvement of p38 mitogen-activated protein kinase in the regulation of platelet-derived growth factor
GONG Xiaowei, WEI Jie, LI Yusheng, CHENG Weiwei, DENG Peng, JIANG Yong
Journal Article
Human menstrual blood-derived stem cells alleviate autoimmune hepatitis via JNK/MAPK signaling pathway and
Journal Article
Mechanisms of connective tissue formation and blocks of mitogen activated protein kinase
Irina A SHURYGINA, Michael G SHURYGIN, Nataliya I AYUSHINOVA, Galina B GRANINA, Nikolay V ZELENIN
Journal Article
The role of protein kinase C epsilon in neural signal transduction and neurogenic diseases
Yuan CHEN, Qi TIAN
Journal Article
Effect of inhibiting tyrosine kinase Src expression on protein phosphatase 2A and tau phosphorylation
LIU Rong, ZENG Ji, ZHOU Xinwen, WANG Jianzhi, PEI Jinjing
Journal Article
Protective effect of tanshinone II A on signal transduction system protein kinase B in rats with myocardial
Enyuan TU MD, Yongjun PAN MM, Kang ZHENG MM, Zhaohua WANG MD, Qiansheng LIANG MD, Guangtian YANG MD,
Journal Article
Inhibition of protein kinase B by Palmitate in the insulin signaling of HepG2 cells and the preventive
XIA Yanzhi, WAN Xuedong, DUAN Qiuhong, HE Shansu, WANG Ximing
Journal Article
Fate of proteins of waste activated sludge during thermal alkali pretreatment in terms of sludge protein
Xiaoli Song, Zhenghua Shi, Xiufen Li, Xinhua Wang, Yueping Ren
Journal Article
Effect of PRAK gene knockout on the proliferation of mouse embryonic fibroblasts
Xiaowei GONG MD, PhD, Xiaoyan MING MD, Xu WANG MM, Daan WANG MD, Peng DENG MM, Yong JIANG MD, PhD, Aihua LIU MD, PhD,
Journal Article
Proteomics study of Mycoplasma pneumoniae pneumonia reveals the Fc fragment of the IgG-binding protein
Journal Article
Gene and protein expression of proteinase-activated receptor-1, 2 in a murine model of acute graft host
Quan LI MD , Weiming LI MD , Ping ZOU MD , Jian ZHANG BM ,
Journal Article
Effects of phosphatidylinositol 3-kinase inhibitor on human cervical carcinoma cells
Yuan ZHANG MD , Xiaoyan ZHANG MM , Yanhui LI MM , Xuan DU MM , Zehua WANG MD, PhD , Hongbo WANG MD ,
Journal Article