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Improvement in the synthesis of 2-(5-amino-1,2,4-thiadiazol-3-yl)-2-(Z)-methoxyiminoacetic acid 2-benzothiazolyl

GAO Shihao, SUN Chenghui, ZHAO Xinqi, GAO Changquan

Frontiers of Chemical Science and Engineering 2008, Volume 2, Issue 1,   Pages 80-84 doi: 10.1007/s11705-008-0017-0

Abstract: 2-(5-Amino-1,2,4-thiadiazol-3-yl)-2-(Z)-methoxyiminoacetic acid 2-benzothiazolyl thioester(III), an importantintermediate of the fourth generation cephalosporins, was efficiently synthesized by reacting 2-(5-amino-1Using 1,2-dichloroethane as solvent, triphenylphosphine as reducer, and triethylamine as catalyst, (I

Keywords： 5-Amino-1     2     4-thiadiazol-3-yl     1     2-dichloroethane     important intermediate     2-benzothiazolyl thioester     temperature    

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Controlled drug release of 5-amino salicylic acid by poly(2-hydroxyethylmethacrylate) grafted agar

G. Usha RANI,Kartick Prasad DEY,Srijita BHARTI,Sumit MISHRA

Frontiers of Chemical Science and Engineering 2014, Volume 8, Issue 4,   Pages 465-470 doi: 10.1007/s11705-014-1452-8

Abstract: (2-hydroxyethylmethacrylate) grafted agar (Ag-g-P(HEMA)) as a matrix for the controlled release of 5-

Keywords： agar     controlled drug release     5-Amino salicylic acid     poly(2-hydroxyethylmethacrylate) grafted agar    

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Encapsulation of 2-amino-2-methyl-1-propanol with tetraethyl orthosilicate for CO2 capture

Sidra Rama, Yan Zhang, Fideline Tchuenbou-Magaia, Yulong Ding, Yongliang Li

Frontiers of Chemical Science and Engineering 2019, Volume 13, Issue 4,   Pages 672-683 doi: 10.1007/s11705-019-1856-6

Abstract: The conventional emulsion technique was selected for the microcapsule formulation by using 2-amino-2-methyl-1-propanol (AMP) as the core sorbent and silicon dioxide as the shell.

Keywords： carbon capture     microencapsulated sorbents     emulsion technique     low temperature adsorption and absorption    

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Catalytic conversion of biomass-derived compounds to various amino acids: status and perspectives

Frontiers of Chemical Science and Engineering 2023, Volume 17, Issue 7,   Pages 817-829 doi: 10.1007/s11705-022-2254-z

Abstract: Amino acids are important nitrogen-containing chemicals that have a variety of applications.Currently, fermentation is the widely employed method to produce amino acids; however, the products aremostly limited to natural amino acids in the L-configuration.Catalytic synthesis is an alternative approach for the synthesis of amino acids with different typesMaking full use of inherent nitrogen in biomass (i.e., chitin and protein) to produce amino acids avoids

Keywords： biomass     amino acids     chitin     nitrogen-containing compounds     lignocellulose    

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Novel variants in LAMA3 and COL7A1 and recurrent variant in KRT5 underlying epidermolysis bullosa in

Frontiers of Medicine 2022, Volume 16, Issue 5,   Pages 808-814 doi: 10.1007/s11684-021-0878-x

Abstract: nonsense variant (c.47G>A, p.W16*) in LAMA3, a known recurrent variant (c.74C>T, p.P25L) in KRT5A, p.G2366D; c.8569G>T, p.E2857*; c.3625_3635del, p.S1209fs) variants in COL7A1

Keywords： epidermolysis bullosa     LAMA3     COL7A1     KRT5     Chinese families    

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Netrin-1 works with UNC5B to regulate angiogenesis in diabetic kidney disease

Xiaojing Jiao, Dong Zhang, Quan Hong, Lei Yan, Qiuxia Han, Fengmin Shao, Guangyan Cai, Xiangmei Chen, Hanyu Zhu

Frontiers of Medicine 2020, Volume 14, Issue 3,   Pages 293-304 doi: 10.1007/s11684-019-0715-7

Abstract: Netrin-1, an axon guidance factor, and its receptor UNC5B play important roles in axonal developmentNetrin-1 and UNC5B were upregulated in streptozotocin-induced DKD Wistar rats, and their expression wasNetrin-1 treatment also eliminated the pro-angiogenic effects of exogenous VEGF-165 on UNC5B-silencedThese results indicate that UNC5B antagonizes netrin-1 and that UNC5B upregulation contributes partlyTherefore, introducing exogenous netrin-1 and depleting endogenous UNC5B are potential strategies for

Keywords： netrin-1     VEGF-165     UNC5B     angiogenesis     diabetic kidney disease    

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Texture branch network for chronic kidney disease screening based on ultrasound images Research Articles

Peng-yi Hao, Zhen-yu Xu, Shu-yuan Tian, Fu-li Wu, Wei Chen, Jian Wu, Xiao-nan Luo,fuliwu@zjut.edu.cn

Frontiers of Information Technology & Electronic Engineering 2020, Volume 21, Issue 8,   Pages 1119-1266 doi: 10.1631/FITEE.1900210

Abstract: (CKD) is a widespread renal disease throughout the world. Once it develops to the advanced stage, serious complications and high risk of death will follow. Hence, early screening is crucial for the treatment of CKD. Since ultrasonography has no side effects and enables radiologists to dynamically observe the morphology and pathological features of the kidney, it is commonly used for kidney examination. In this study, we propose a novel convolutional neural network (CNN) framework named the to screen CKD based on images. This introduces a texture branch into a typical CNN to extract and optimize texture features. The model can automatically generate texture features and deep features from input images, and use the fused information as the basis of classification. Furthermore, we train the base part of the network by means of , and conduct experiments on a dataset with 226 images. Experimental results demonstrate the effectiveness of the proposed approach, achieving an accuracy of 96.01% and a sensitivity of 99.44%.

Keywords： 慢性肾脏病；超声；纹理分支网络；迁移学习    

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A replenishment for resource reserves：functional reserves— Replacing 1/10~1/5 strategic oil reserve with

Jin Yong,Chen Bingzhen

Strategic Study of CAE 2008, Volume 10, Issue 11,   Pages 4-6

Abstract:

The strategic oil reserve is very important for every large country in the world. In order to meet the basic requirement of the state safety, 3 months strategic oil reserve in every large country was proposed by the different international organizations such as UN, EU, etc. For China, the total amount of strategic oil reserve must be up to about 30 to 90 millions. It is very difficult to achieve it without enormous capita in short time. Based on a new conception as "function reserve" to replenish the "resource reserve", this goal could be more easy to be accomplished.Namely, storing more methanols replaces some percentage of oil. Moreover, the state safety should be ensured. This topic is discussed in the article in detail.

Keywords： function store     strategical oil store     methanol    

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Endemicity of H9N2 and H5N1 avian influenza viruses in poultry in China poses a serious threat to poultry

Jiao HU,Xiufan LIU

Frontiers of Agricultural Science and Engineering 2016, Volume 3, Issue 1,   Pages 11-24 doi: 10.15302/J-FASE-2016092

Abstract: The H9N2 and H5N1 avian influenza viruses (AIVs) have been circulating in poultry in China and becomeinfluenza viruses, such as the well-known viruses of the highly pathogenic avian influenza (HPAI) H5N2

Keywords： avian influenza virus     H9N2     H5N1     novel viruses     public health    

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A novel grey wolf optimizer and its applications in 5G frequency selection surface design Research Article

Zhihao HE, Gang JIN, Yingjun WANG

Frontiers of Information Technology & Electronic Engineering 2022, Volume 23, Issue 9,   Pages 1338-1353 doi: 10.1631/FITEE.2100580

Abstract: In this paper, we propose a self-adaptive (SAGWO) combined with a novel optimization model of a 5GDue to its global searchability, SAGWO is suitable for solving the optimization problem of a 5G FSS that

Keywords： Grey wolf optimizer     Fifth-generation wireless communication system (5G)     Frequency selection surface    

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Unidirectional and stage-dependent roles of Notch1 in Wnt-responsive Lgr5

Hui Jiang, Shan Zeng, Wenli Ni, Yan Chen, Wenyan Li

Frontiers of Medicine 2019, Volume 13, Issue 6,   Pages 705-712 doi: 10.1007/s11684-019-0703-y

Abstract: specifically in Wnt-responsive Lgr5 progenitors during different cochlear development stages.We found that the downregulation of Notch1 in Lgr5 cells from embryonic day (E) 14.5 to E18.5 can driveNo effect was observed on the upregulation or downregulation of Notch1 in Lgr5 cells from E10.5 to E14.5We concluded that the roles of Notch1 in Wnt-responsive Lgr5 cells are unidirectional and stage dependentand Notch1 serves as a negative regulator for Lgr5 progenitor activation during cochlear differentiation

Keywords： inner ear     cochlear     Wnt     Notch     Lgr5     auditory system    

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Insights into the changes of amino acids, microbial community, and enzymatic activities related with

Frontiers of Environmental Science & Engineering 2023, Volume 17, Issue 3, doi: 10.1007/s11783-023-1635-y

Abstract:

● The highest seed germination index was achieved at 0.3 g/g total solids of food waste.

Keywords： Composting     Food waste     Amino acids     Microbial community     Enzymatic activity     Nutrient quality    

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A high-isolation coupled-fed building block for metal-rimmed 5G smartphones Correspondence

Aidi REN, Chengwei YU, Lixia YANG, Wei CUI, Zhixiang HUANG, Ying LIU

Frontiers of Information Technology & Electronic Engineering 2023, Volume 24, Issue 11,   Pages 1657-1664 doi: 10.1631/FITEE.2300203

Abstract: A dual-antenna building block with high isolation is presented for metal-rimmed fifth-generation (5G)
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Immobilization of penicillin G acylase onto amino-modified silica hydrogel

Weibing Dong, Huining HE, Junbo Gong, Victor C. YANG,

Frontiers of Chemical Science and Engineering 2010, Volume 4, Issue 1,   Pages 87-90 doi: 10.1007/s11705-009-0298-y

Abstract: Amino-modified silica hydrogel (N-MSHG) was prepared by a simple sol-gel processing via the co-condensationThe results showed that the amino-modified gel was a mesoporous material with an average pore size of

Keywords： gravimetric     amino-modified     efficient     Amino-modified     amoxicillin    

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Insulin resistance and the metabolism of branched-chain amino acids

Jingyi Lu, Guoxiang Xie, Weiping Jia, Wei Jia

Frontiers of Medicine 2013, Volume 7, Issue 1,   Pages 53-59 doi: 10.1007/s11684-013-0255-5

Abstract: Branched-chain amino acids (BCAAs), namely valine, leucine and isoleucine, are among the nine essentialamino acids, accounting for 35% of the essential amino acids in muscle proteins and 40% of the preformedamino acids required by mammals.The BCAAs are particularly responsive to the inhibitory insulin action on amino acid release by skeletal

Keywords： branched-chain amino acids     leucine     isoleucine     valine     insulin resistance    

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Title Author Date Type Operation

Improvement in the synthesis of 2-(5-amino-1,2,4-thiadiazol-3-yl)-2-(Z)-methoxyiminoacetic acid 2-benzothiazolyl

GAO Shihao, SUN Chenghui, ZHAO Xinqi, GAO Changquan

Journal Article

Controlled drug release of 5-amino salicylic acid by poly(2-hydroxyethylmethacrylate) grafted agar

G. Usha RANI,Kartick Prasad DEY,Srijita BHARTI,Sumit MISHRA

Journal Article

Encapsulation of 2-amino-2-methyl-1-propanol with tetraethyl orthosilicate for CO2 capture

Sidra Rama, Yan Zhang, Fideline Tchuenbou-Magaia, Yulong Ding, Yongliang Li

Journal Article

Catalytic conversion of biomass-derived compounds to various amino acids: status and perspectives

Journal Article

Novel variants in LAMA3 and COL7A1 and recurrent variant in KRT5 underlying epidermolysis bullosa in

Journal Article

Netrin-1 works with UNC5B to regulate angiogenesis in diabetic kidney disease

Xiaojing Jiao, Dong Zhang, Quan Hong, Lei Yan, Qiuxia Han, Fengmin Shao, Guangyan Cai, Xiangmei Chen, Hanyu Zhu

Journal Article

Texture branch network for chronic kidney disease screening based on ultrasound images

Peng-yi Hao, Zhen-yu Xu, Shu-yuan Tian, Fu-li Wu, Wei Chen, Jian Wu, Xiao-nan Luo,fuliwu@zjut.edu.cn

Journal Article

A replenishment for resource reserves：functional reserves— Replacing 1/10~1/5 strategic oil reserve with

Jin Yong,Chen Bingzhen

Journal Article

Endemicity of H9N2 and H5N1 avian influenza viruses in poultry in China poses a serious threat to poultry

Jiao HU,Xiufan LIU

Journal Article

A novel grey wolf optimizer and its applications in 5G frequency selection surface design

Zhihao HE, Gang JIN, Yingjun WANG

Journal Article

Unidirectional and stage-dependent roles of Notch1 in Wnt-responsive Lgr5

Hui Jiang, Shan Zeng, Wenli Ni, Yan Chen, Wenyan Li

Journal Article

Insights into the changes of amino acids, microbial community, and enzymatic activities related with

Journal Article

A high-isolation coupled-fed building block for metal-rimmed 5G smartphones

Aidi REN, Chengwei YU, Lixia YANG, Wei CUI, Zhixiang HUANG, Ying LIU

Journal Article

Immobilization of penicillin G acylase onto amino-modified silica hydrogel

Weibing Dong, Huining HE, Junbo Gong, Victor C. YANG,

Journal Article

Insulin resistance and the metabolism of branched-chain amino acids

Jingyi Lu, Guoxiang Xie, Weiping Jia, Wei Jia

Journal Article