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Effects of hydralazine and valproate on the expression of E-cadherin gene and the invasiveness of QBC

Hong LI, Shaoqin CHEN, Yi SHU, Yongjun CHEN, Ying SU, Xin WANG, Shengquan ZOU

Frontiers of Medicine 2009, Volume 3, Issue 2,   Pages 153-157 doi: 10.1007/s11684-009-0034-5

Abstract: To clarify the effect of DNA methylation and histone deacetylase inhibitors on the expression of the E-cadherinThe mRNA expression of E-cadherin was examined with reverse transcription-polymerase chain reaction (It was found that the promoter region of the E-cadherin gene of QBC cells was hypermethylated.What’s more, it was confirmed that the E-cadherin gene of QBC cells could not be transcriptionally reactivatedHowever, using valproate and hydralazine in combination could result in robust reexpression of the E-cadherin

Keywords： DNA methylation inhibitor     histone deacetylase inhibitor     bile duct carcinoma     E-cadherin    

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Overexpressed miR-9 promotes tumor metastasis via targeting E-cadherin in serous ovarian cancer

Bo Zhou, Hongbin Xu, Meng Xia, Chaoyang Sun, Na Li, Ensong Guo, Lili Guo, Wanying Shan, Hao Lu, Yifan Wu, Yuan Li, Degui Yang, Danhui Weng, Li Meng, Junbo Hu, Ding Ma, Gang Chen, Kezhen Li

Frontiers of Medicine 2017, Volume 11, Issue 2,   Pages 214-222 doi: 10.1007/s11684-017-0518-7

Abstract: In this study, results from the bioinformatics analysis show that the 3′-UTR of the E-cadherinLuciferase reporter assay results confirmed that miR-9 could directly target this 3′-UTR. miR-9 and E-cadherinImmunofluorescence technique was used to analyze the expression and subcellular localization of E-cadherinUpregulation of miR-9 could downregulate the expression of E-cadherin but upregulate the expression ofThus, our study demonstrates that miR-9 may promote ovarian cancer metastasis via targeting E-cadherin

Keywords： ovarian cancer     metastasis     miR-9     E-cadherin    

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Effects of hypoxia inducible factor-1alpha siRNA on the invasion of human Hela cells and expression of related proteins

Bin YANG MS , Xianglin YUAN , Yanmei ZOU , Qingsong XI , Guoxian LONG , Qiang FU , Guangyuan HU MM ,

Frontiers of Medicine 2009, Volume 3, Issue 3,   Pages 303-308 doi: 10.1007/s11684-009-0060-3

Abstract: The expression of HIF-1α, E-cadherin, β-catenin, and actin was detected using Western blot.The expression of HIF-1α, E-cadherin, and β-catenin in tumor grafts was assayed immunohistochemicallyWestern blot results revealed that the bands of HIF-1α, E-cadherin, β-catenin, and actin proteinsThe expression of E-cadherin, β-catenin, and actin was detected in the H group under hypoxia forhypoxia on the invasion of human cervical cancer Hela cells and the expression of related proteins (E-cadherin

Keywords： hypoxia     actin     β     -catenin     E-cadherin     invasion    

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Dysregulation of β-catenin by hepatitis B virus X protein in HBV-infected human hepatocellular carcinomas

Lei CHEN, Liang HU, Liang LI, Yuan LIU, Qian-Qian TU, Yan-Xin CHANG, He-Xin YAN, Meng-Chao WU, Hong-Yang WANG,

Frontiers of Medicine 2010, Volume 4, Issue 4,   Pages 399-411 doi: 10.1007/s11684-010-0170-y

Abstract: The expression levels of wild-type β-catenin and E-cadherin were decreased in HepG2 cells expressing

Keywords： hepatocellular carcinoma     hepatitis B virus X protein     β     -catenin     cell adhesion     E-cadherin     transcriptional    

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Sustainability of metal recovery from E-waste

Biswajit Debnath, Ranjana Chowdhury, Sadhan Kumar Ghosh

Frontiers of Environmental Science & Engineering 2018, Volume 12, Issue 6, doi: 10.1007/s11783-018-1044-9

Abstract:

Metal recovery techniques from electronic waste reported in literature.

Metal recovery processes followed in Industries from electronic waste.

Sustainability analysis of metal recovery processes from electronic waste.

Keywords： E-waste     Metal recovery     Metal Recovery from E-waste (MREW)     Sustainability    

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Molecular dynamics modeling of a single diamond abrasive grain in grinding

SAVVOPOULOS,Nikolaos E. KARKALOS,Dimitrios E. MANOLAKOS

Frontiers of Mechanical Engineering 2015, Volume 10, Issue 2,   Pages 168-175 doi: 10.1007/s11465-015-0337-y

Abstract:

In this paper the nano-metric simulation of grinding of copper with diamond abrasive grains, using the molecular dynamics (MD) method, is considered. An MD model of nano-scale grinding, where a single diamond abrasive grain performs cutting of a copper workpiece, is presented. The Morse potential function is used to simulate the interactions between the atoms involved in the procedure. In the proposed model, the abrasive grain follows a curved path with decreasing depth of cut within the workpiece to simulate the actual material removal process. Three different initial depths of cut, namely 4 ?, 8 ? and 12 ?, are tested, and the influence of the depth of cut on chip formation, cutting forces and workpiece temperatures are thoroughly investigated. The simulation results indicate that with the increase of the initial depth of cut, average cutting forces also increase and therefore the temperatures on the machined surface and within the workpiece increase as well. Furthermore, the effects of the different values of the simulation variables on the chip formation mechanism are studied and discussed. With the appropriate modifications, the proposed model can be used for the simulation of various nano-machining processes and operations, in which continuum mechanics cannot be applied or experimental techniques are subjected to limitations.

Keywords： molecular dynamics     abrasive process     chip formation     cutting force     temperature    

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risks of heavy metals, polybrominated diphenyl ethers, and polychlorinated dibenzo-dioxins/furans at e-waste

Frontiers of Environmental Science & Engineering 2023, Volume 17, Issue 7, doi: 10.1007/s11783-023-1679-z

Abstract:

● Heavy metals and organic toxins may persist in legacy sites for a long time.

Keywords： E-waste     Human health risk     Organ risk     Heavy metal toxicity     PBDE     PCDD/F    

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Policy options for Agriculture Green Development by farmers in China

Laurence E. D. SMITH

Frontiers of Agricultural Science and Engineering 2020, Volume 7, Issue 1,   Pages 90-97 doi: 10.15302/J-FASE-2019290

Abstract:

Farmers are the key agents who manage land and water. Agriculture Green Development (AGD) requires a transformation in farming from high resource consumption and environmental cost to sustainable intensification with high productivity, high resource use efficiency and low environmental risk. This paper analyzes the public policy challenge of AGD and makes the case for a location-sensitive policy mix made up of regulation, advice provision, voluntarism and targeted incentives. The public agricultural extension service in China is a key resource, but one that requires reorientation and reform with the aim of better balancing high farm productivity with environmental protection.

Keywords： agriculture     environment     development     incentives     policy     regulation    

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The Use of Data Mining Techniques in Rockburst Risk Assessment

Luis Ribeiro e Sousa, Tiago Miranda, Rita Leal e Sousa, Joaquim Tinoco

Engineering 2017, Volume 3, Issue 4,   Pages 552-558 doi: 10.1016/J.ENG.2017.04.002

Abstract:

Rockburst is an important phenomenon that has affected many deep underground mines around the world. An understanding of this phenomenon is relevant to the management of such events, which can lead to saving both costs and lives. Laboratory experiments are one way to obtain a deeper and better understanding of the mechanisms of rockburst. In a previous study by these authors, a database of rockburst laboratory tests was created; in addition, with the use of data mining (DM) techniques, models to predict rockburst maximum stress and rockburst risk indexes were developed. In this paper, we focus on the analysis of a database of in situ cases of rockburst in order to build influence diagrams, list the factors that interact in the occurrence of rockburst, and understand the relationships between these factors. The in situ rockburst database was further analyzed using different DM techniques ranging from artificial neural networks (ANNs) to naive Bayesian classifiers. The aim was to predict the type of rockburst—that is, the rockburst level—based on geologic and construction characteristics of the mine or tunnel. Conclusions are drawn at the end of the paper.

Keywords： Rockburst     Data mining     Bayesian networks     In situ database    

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Investigation of electrochemical degradation and application of e-paper dyes in organic solvents

Luhai LI, Ming WANG, Yi FANG, Shunan QIAO

Frontiers of Chemical Science and Engineering 2009, Volume 3, Issue 2,   Pages 182-185 doi: 10.1007/s11705-009-0062-3

Abstract: A dye electrophoresis in organic solution flexible prototype e-paper display was formed and the display

Keywords： electrochemical degradation     electrophoresis     e-paper     oxidized azobenzene group    

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Zero E-waste: Regulatory impediments and blockchain imperatives

Mengjun Chen, Oladele A. Ogunseitan

Frontiers of Environmental Science & Engineering 2021, Volume 15, Issue 6, doi: 10.1007/s11783-021-1402-x

Abstract: Electronic waste (E-waste), the fastest growing category of solid hazardous waste presents various uniqueElectronic product repair, reuse and remanufacture (3re) are crucial for effective source reduction of E-wastediscs (CDs) to identify the challenges and to explore solutions for managing the risks associated with E-wasterefurbish fake/counterfeit product and copyright exhaustion, are proposed to accelerate source reduction in E-waste

Keywords： Blockchain     E-waste     Regulatory Policy     Copyright Laws     Repair-Reuse-Remanufacture     Toxicity    

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Spent rechargeable lithium batteries in e-waste: composition and its implications

Xianlai ZENG,Jinhui LI

Frontiers of Environmental Science & Engineering 2014, Volume 8, Issue 5,   Pages 792-796 doi: 10.1007/s11783-014-0705-6

Abstract: The amount of spent rechargeable lithium batteries (RLBs) is growing rapidly owing to wide application of these batteries in portable electronic devices and electric vehicles, which obliges that spent RLBs should be handled properly. Identification of spent RLBs can supply fundamental information for spent RLBs recycling. This study aimed to determine the differences of physical components and chemical compositions among various spent RLBs. All the samplings of RLBs were rigorously dismantled and measured by an inductive coupled plasma atomic emission spectrometer. The results indicate that the average of total weight of the separator, the anode and the cathode accounted for over 60% of all the RLBs. The weight ratio of valuable metals ranged from 26% to 76%, and approximately 20% of total weight was Cu and Al. Moreover, no significant differences were found among different manufacturers, applications, and electrolyte types. And regarding portable electronic devices, there is also no significant difference in the Co-Li concentration ratios in the leaching liquid of RLBs.

Keywords： rechargeable lithium batteries     e-waste     physical components     difference analysis     recycling    

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An improved design method to predict the E-modulus and strength of FRP composites at different temperatures

Mohammed FARUQI, Gobishanker RAJASKANTHAN, Breanna BAILEY, Francisco AGUINIGA

Frontiers of Structural and Civil Engineering 2022, Volume 16, Issue 12,   Pages 1653-1653 doi: 10.1007/s11709-019-0578-7

Abstract: However, the E-modulus and strength of such members at high service temperatures is still unknown.Thus, this paper proposes design methods for calculating the E-modulus and strength of FRP members atIt was found that the proposed design methods conservatively estimate the E-modulus and strength of FRP

Keywords： concrete     fiber reinforced polymer     E-modulus     strength     temperatures    

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APPLE SUMO E3 LIGASE MDSIZ1 NEGATIVELY REGULATES DROUGHT TOLERANCE

Frontiers of Agricultural Science and Engineering 2021, Volume 8, Issue 4,   Pages 662-662 doi: 10.15302/J-FASE-2021408

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Electro-catalytic activity of CeO modified graphite felt for carbamazepine degradation via E-peroxone

Frontiers of Environmental Science & Engineering 2021, Volume 15, Issue 6, doi: 10.1007/s11783-021-1410-x

Abstract:

•CeOx/GF-EP process had the better degradation efficiency than GF-EP process.

Keywords： E-peroxone     CeOx     Graphite felt     Carbamazepine     Mineralization    

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Title Author Date Type Operation

Effects of hydralazine and valproate on the expression of E-cadherin gene and the invasiveness of QBC

Hong LI, Shaoqin CHEN, Yi SHU, Yongjun CHEN, Ying SU, Xin WANG, Shengquan ZOU

Journal Article

Overexpressed miR-9 promotes tumor metastasis via targeting E-cadherin in serous ovarian cancer

Bo Zhou, Hongbin Xu, Meng Xia, Chaoyang Sun, Na Li, Ensong Guo, Lili Guo, Wanying Shan, Hao Lu, Yifan Wu, Yuan Li, Degui Yang, Danhui Weng, Li Meng, Junbo Hu, Ding Ma, Gang Chen, Kezhen Li

Journal Article

Effects of hypoxia inducible factor-1alpha siRNA on the invasion of human Hela cells and expression of related proteins

Bin YANG MS , Xianglin YUAN , Yanmei ZOU , Qingsong XI , Guoxian LONG , Qiang FU , Guangyuan HU MM ,

Journal Article

Dysregulation of β-catenin by hepatitis B virus X protein in HBV-infected human hepatocellular carcinomas

Lei CHEN, Liang HU, Liang LI, Yuan LIU, Qian-Qian TU, Yan-Xin CHANG, He-Xin YAN, Meng-Chao WU, Hong-Yang WANG,

Journal Article

Sustainability of metal recovery from E-waste

Biswajit Debnath, Ranjana Chowdhury, Sadhan Kumar Ghosh

Journal Article

Molecular dynamics modeling of a single diamond abrasive grain in grinding

SAVVOPOULOS,Nikolaos E. KARKALOS,Dimitrios E. MANOLAKOS

Journal Article

risks of heavy metals, polybrominated diphenyl ethers, and polychlorinated dibenzo-dioxins/furans at e-waste

Journal Article

Policy options for Agriculture Green Development by farmers in China

Laurence E. D. SMITH

Journal Article

The Use of Data Mining Techniques in Rockburst Risk Assessment

Luis Ribeiro e Sousa, Tiago Miranda, Rita Leal e Sousa, Joaquim Tinoco

Journal Article

Investigation of electrochemical degradation and application of e-paper dyes in organic solvents

Luhai LI, Ming WANG, Yi FANG, Shunan QIAO

Journal Article

Zero E-waste: Regulatory impediments and blockchain imperatives

Mengjun Chen, Oladele A. Ogunseitan

Journal Article

Spent rechargeable lithium batteries in e-waste: composition and its implications

Xianlai ZENG,Jinhui LI

Journal Article

An improved design method to predict the E-modulus and strength of FRP composites at different temperatures

Mohammed FARUQI, Gobishanker RAJASKANTHAN, Breanna BAILEY, Francisco AGUINIGA

Journal Article

APPLE SUMO E3 LIGASE MDSIZ1 NEGATIVELY REGULATES DROUGHT TOLERANCE

Journal Article

Electro-catalytic activity of CeO modified graphite felt for carbamazepine degradation via E-peroxone

Journal Article